Predicting early functional outcomes in aneurysmal subarachnoid hemorrhage in endovascular coiling and surgical clipping.

Objectives: This study aimed to evaluate early functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) treated with either endovascular coiling or surgical clipping and to develop predictive models tailored to each treatment modality. Materials and methods: Patients diagnosed with aSAH were retrospectively enrolled from two hospitals in China between January 1, 2015, and December 31, 2022. Based on the treatment approach, patients were divided into two groups: endovascular coiling and surgical clipping. Independent risk factors were identified using least absolute shrinkage and selection operator (LASSO) regression followed by multivariate logistic regression. The relative contribution of each significant factor was calculated, and nomograms were constructed accordingly. Model performance was subsequently assessed through validation analyses. Results: Multivariate analysis identified Hunt-Hess grade, Glasgow Coma Scale (GCS) score, modified Fisher Scale (mFS), D-dimer, age, and body temperature as independent predictors of early functional outcomes following endovascular coiling (all Conclusion: This study developed predictive nomogram models for early functional outcomes of aSAH patients undergoing endovascular coiling or surgical clipping treatments, emphasizing the importance of scoring systems and clinical parameters (such as D-dimer), demonstrating strong clinical utility.