Evidence map›Paper›PMID 40401013›Full record

ArticleNeurology. Genetics2025

Madeline Komar, Jashanpreet Sidhu, Jiju Joseph, Ashna Kumar, David J A Callen, Ronit Mesterman, Rajesh Ramachandrannair, Kevin C Jones, Brandon F Meaney, Sonali Singh and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Madeline KomarDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0009-0001-1842-9898
Jashanpreet SidhuDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0009-9094-3566
Jiju JosephPediatric Neurology Unit, Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0006-5569-921X
Ashna KumarDivision of Neurology, Department of Paediatrics, AIIMS, Jodhpur, Rajasthan, India.ORCID https://orcid.org/0000-0001-7086-526X
David J A CallenDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0009-0006-6877-3351
Ronit MestermanDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0009-0000-2820-3553
Rajesh RamachandrannairDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-0368-8640
Kevin C JonesDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0002-2358-8308
Brandon F MeaneyDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-0704-3583
Sonali SinghDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0004-6880-9196
Lyndsey McRaeDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0004-9140-0815
Vann ChauDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8260-8738
Suvasini SharmaDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3135-3306
Elizabeth J DonnerDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-1126-0548
Rekha AaronDepartment of Medical Genetics, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-6376-8071
Sumita DandaDepartment of Medical Genetics, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-8973-370X
Maya ThomasPediatric Neurology Unit, Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-1883-4631
Lokesh SainiDivision of Neurology, Department of Paediatrics, AIIMS, Jodhpur, Rajasthan, India.ORCID https://orcid.org/0000-0003-3153-0736
Gregory CostainGenetics and Genome Biology Program, SickKids Research Institute, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-0099-9945
Sangeetha YoganathanPediatric Neurology Unit, Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0001-1429-8392
Puneet JainDivision of Neurology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-6009-0859
Robyn WhitneyDivision of Neurology, Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0001-6851-0646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Pathogenic variants in the Methods: All children with epilepsy and either a pathogenic Results: Forty children were identified, and 24 were male (n = 24/40, 60%). The median age at seizure onset was 5 months (IQR 4, 6) (range 2-150 months). Bilateral tonic-clonic (BTC) (n = 22/40, 55%) and focal motor seizures with impaired awareness evolving to BTC seizures (n = 9/40, 23%) were most common. Thirty-six children (n = 36/40, 90%) had pathogenic Discussion: Pathogenic

Identifiers

PMID40401013
PMCPMC12094785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.