Evidence map›Paper›PMID 40400997›Full record

ArticleAmerican journal of clinical and experimental urology2025

DeepSeek vs ChatGPT: a comparison study of their performance in answering prostate cancer radiotherapy questions in multiple languages.

Peng-Wei Luo, Ji-Wen Liu, Xi Xie, Jia-Wei Jiang, Xin-Yu Huo, Zhen-Lin Chen, Zhang-Cheng Huang, Shao-Qin Jiang, Meng-Qiang Li

Abstract read
In one paragraph

Article in American journal of clinical and experimental urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Capacity of Understanding the Future Approaches in Cancer Treatment by Multiple Models of Artificial Intelligence.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng-Wei LuoDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.
Ji-Wen LiuDepartment of Urology, The General Hospital of Western Theater Command Chengdu, Sichuan, China.
Xi XieDepartment of Urology, The First Affiliated Hospital of Chengdu Medical College Chengdu, Sichuan, China.
Jia-Wei JiangDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.
Xin-Yu HuoDepartment of Urology, The First Affiliated Hospital of Chengdu Medical College Chengdu, Sichuan, China.
Zhen-Lin ChenDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.
Zhang-Cheng HuangDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.
Shao-Qin JiangDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.
Meng-Qiang LiDepartment of Urology, Fujian Union Hospital, Fujian Medical University Fuzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe medical information generated by large language models (LLM) is crucial for improving patient education and clinical decision-making. This study aims to evaluate the performance of two LLMs (DeepSeek and ChatGPT) in answering questions related to prostate cancer radiotherapy in both Chinese and English environments. Through a comparative analysis, we aim to determine which model can provide higher-quality answers in different language environments.

methodsA structured evaluation framework was developed using a set of clinically relevant questions covering three key domains: foundational knowledge, patient education, and treatment and follow-up care. Responses from DeepSeek and ChatGPT were generated in both English and Chinese and independently assessed by a panel of five oncology specialists using a five-point Likert scale. Statistical analyses, including the Wilcoxon signed-rank test, were performed to compare the models' performance across different linguistic contexts.

resultsThis study ultimately included 33 questions for scoring. In Chinese, DeepSeek outperformed ChatGPT, achieving top ratings (score = 5) in 75.76% vs. 36.36% of responses (P < 0.001), excelling in foundational knowledge (76.92% vs. 38.46%,

conclusionsThis study shows that DeepSeek performs excellently in providing Chinese medical information, while the two models perform similarly in an English environment. These findings underscore the importance of selecting language-specific artificial intelligence (AI) models to enhance the accuracy and reliability of medical AI applications. While both models show promise in supporting patient education and clinical decision-making, human expert review remains necessary to ensure response accuracy and minimize potential misinformation.

Indexed as

Artificial intelligenceChatGPTDeepSeekprostate cancerradiotherapy

Identifiers

PMID40400997
PMCPMC12089221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.