Evidence map›Paper›PMID 40400972›Full record

ArticleJournal of thoracic disease2025

Single versus multisite intercostal nerve block for post-thoracoscopic pain: a prospective observational study.

Bixin Wen, Jinling Yao, Shilong Wang, Binhao Xu, Yuanjing Zhang, Wen Wang, Qiaochu Xu, Li Li, Changhong Liu, Yaqing Huang and 9 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bixin WenChina-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Jinling YaoWisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Shilong WangChina-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Binhao XuChina-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yuanjing ZhangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Wen WangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Qiaochu XuWisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Li LiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Changhong LiuDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Yaqing HuangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Satoshi HanadaDivision of Cardiothoracic Anesthesia, Department of Anesthesia, University of Iowa Roy J. and Lucille A. Carver College of Medicine, IA, USA.
Min WangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Yuhui ShiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Zhenrong ZhangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Chaoyang LiangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Yajun ZhangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Ying ChenWisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Yang YangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Qianli MaDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The analgesic efficacy of intercostal nerve block (ICNB) in adults undergoing thoracic surgery and the optimal extent of nerve block remain unclear. To evaluate the analgesic efficacy of ICNB and the optimal extent of nerve block in adults undergoing thoracoscopic surgery, we conducted a prospective cohort study of post-thoracoscopic pain. Methods: We conducted a prospective observational cohort study to assess the postoperative pain intensity scores and other relevant factors associated with different ICNB techniques for pain management in thoracoscopic surgery in a tertiary hospital in Beijing, China. Postoperative pain management was categorized into three groups: the ICNB single-site injection (ICNB SI) group, in which the third to fifth intercostal nerves were blocked with 1 mL of 0.5% ropivacaine at each costal level; the ICNB incision-specific multi-site injection (ICNB ISMSI) group, in which the third to eighth intercostal nerves were blocked with 1 mL of 0.5% ropivacaine at each costal level; and the non-ICNB anesthesia group, which did not undergo any block. Results: Pain intensity scores (visual analog scale, VAS) in the ICNB SI group were significantly lower than those in the ICNB ISMSI group within 24 hours after surgery (4.9±2.4 Conclusions: Thoracic incision-specific multi-site injections were not superior to single injections of ICNB in terms of post-thoracoscopic analgesia. The single-injection approach (ICNB SI) maintained analgesia for 4 days after thoracoscopic surgery, while the multisite injection (ICNB ISMSI) did not demonstrate this prolonged effect. Further research is needed to elucidate the exact mechanisms underlying these differential analgesic effects in clinical practice.

Indexed as

Intercostal nerve block (ICNB)pain managementthoracic surgeryvisual analog scale (VAS)

Identifiers

PMID40400972
PMCPMC12090104

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.