Evidence map›Paper›PMID 40400950›Full record

ArticleJournal of thoracic disease2025

Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury.

Bob P Hermans, Shoko Vos, Wilson W L Li, Erik H F M van der Heijden, Harry van Goor, Ad F T M Verhagen, Richard P G Ten Broek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bob P HermansDepartment of Cardio-Thoracic Surgery, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Shoko VosDepartment of Pathology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Wilson W L LiDepartment of Cardio-Thoracic Surgery, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Erik H F M van der HeijdenDepartment of Pulmonology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Harry van GoorDepartment of General Surgery, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Ad F T M VerhagenDepartment of Cardio-Thoracic Surgery, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Richard P G Ten BroekDepartment of General Surgery, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A lung sealant based on a porcine gelatin carrier impregnated with N-hydroxysuccinimide ester functionalized poly(2)oxazolines (NHS-POx) and nucleophilically activated polyoxazolines (NU-POx) was shown to be efficacious for lung sealing Methods: Three groups, NHS-POx, fibrin patch (TachoSil Results: The total cell response score was significantly higher for NHS-POx Conclusions: The NHS-POx patch shows a comparable to favorable biocompatibility profile compared to fibrin patch, and is a potent candidate for clinical lung sealing applications.

Indexed as

Air leakin-vivolung sealinglung surgerypolymers

Identifiers

PMID40400950
PMCPMC12090121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.