Evidence map›Paper›PMID 40400937›Full record

ReviewJournal of thoracic disease2025

Expert consensus on cancer treatment-related lung injury.

Xinqing Lin, Hui Guo, Wei Zhao, Min Li, Gen Lin, Qian Chu, Enguo Chen, Liang'an Chen, Rui Chen, Tianqing Chu and 95 more

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

105 authors.

Xinqing Lin *State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Hui Guo *Department of Medical Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wei Zhao *Department of Respiratory and Critical Care Medicine, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Min Li *Department of Respiratory Medicine, Xiangya Cancer Center, Xiangya Hospital, Central South University, Changsha, China.
Gen Lin *Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing, China.
Qian Chu *Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Enguo ChenDepartment of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou, China.
Liang'an ChenDepartment of Medical Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Rui ChenDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Tianqing ChuDepartment of Respiratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Haiyi DengState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yu DengState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Hangming DongChronic Airways Diseases Laboratory, Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wen DongDepartment of Lung Cancer, Tianjin Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Yuchao DongDepartment of Pulmonary and Critical Care Medicine, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China.
Wenfeng FangDepartment of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xin GanDepartment of Respiration, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Liang GongDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of the Army Medical University, Chongqing, China.
Yingying GuState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Qian HanState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yue HaoDepartment of Clinical Trial, Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital), Hangzhou, China.
Yong HeDepartment of Pulmonary and Critical Care Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Chengping HuDepartment of Pulmonary Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jie HuDepartment of Respiratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi HuDepartment of Medical Oncology, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Yongliang JiangDepartment of Respiratory Medicine, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Yang JinDepartment of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fen LanDepartment of Respiratory Medicine, The Second Affiliated Hospital of Zhejiang University of Medicine, Hangzhou, China.
Weimin LiDepartment of Respiratory and Critical Care Medicine, Clinical Research Center for Respiratory Disease, West China Hospital, Sichuan University, Chengdu, China.
Weifeng LiDepartment of Respiratory Medicine, General Hospital of Guangzhou Military Command of PLA, Guangzhou, China.
Wenhua LiangState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Anwen LiuDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Dan LiuDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Ming LiuState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Mengjie LiuPhase I Clinical Trial Research Ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhuo LiuDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Zhefeng LiuDepartment of Oncology, General Hospital of Chinese PLA, Beijing, China.
Qun LuoState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Liyun MiaoDepartment of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Chuanyong MuDepartment of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.
Pinhua PanDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China.
Ping PengCancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jianwen QinDepartment of Respiratory and Critical Care Medicine, Tianjin Chest Hospital, Tianjin, China.
Yinyin QinState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Panxiao ShenState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Minhua ShiDepartment of Respiratory Medicine, The Second Affiliated Hospital of Suzhou University, Suzhou, China.
Yong SongDepartment of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing, China.
Chunxia SuDepartment of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Jin SuDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xin SuDepartment of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Xiaowu TanPulmonary and Critical Care Medicine, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Kejing TangDivision of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, Institute of Pulmonary Diseases, Sun Yat-sen University, Guangzhou, China.
Xiaomei TangDepartment of Oncology, Jiangxi Provincial Chest Hospital, Nanchang, China.
Panwen TianLung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China.
Binchao WangGuangdong Lung Cancer Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, China.
Huijuan WangDepartment of Medical Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Kai WangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Zhejiang University of Medicine, Hangzhou, China.
Mengzhao WangDepartment of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Beijing, China.
Qi WangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Wenxian WangDepartment of Chemotherapy, Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital), Hangzhou, China.
Zhijie WangDepartment of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Di WuDepartment of Respiratory Medicine, Shenzhen People's Hospital, Shenzhen, China.
Fei XuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yan XuDepartment of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Beijing, China.
Chunwei XuHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.
Zhanhong XieState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Xiaohong XieState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Boyan YangDepartment of Comprehensive Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Meng YangDepartment of Respiratory Disease, China-Japan Friendship Hospital, Beijing, China.
Feng YeDepartment of Medical Oncology, Xiamen Key Laboratory of Antitumor Drug Transformation Research, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Xiaoqun YeDepartment of Respiratory Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zongyang YuDepartment of Pulmonary and Critical Care Medicine, The 900th Hospital of Joint Logistic Support Force, PLA, Fuzhou, China.
Jian ZhangDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jianqing ZhangSecond Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Kunming Medical University, Kunming, China.
Xiaoju ZhangDepartment of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
Fei ZhaoDepartment of Respiratory and Critical Care Medicine, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Changsha, China.
Xiaobin ZhengDepartment of Thoracic Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Bo ZhuChongqing Key Laboratory of Immunotherapy, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Zhengfei ZhuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Jianya ZhouDepartment of Respiratory Disease, Thoracic Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Jianying ZhouDepartment of Respiratory Diseases, The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou, China.
Min ZhouDepartment of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qing ZhouGuangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Zihua ZouDepartment of Thoracic Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Biniam KidaneSection of Thoracic Surgery, Department of Surgery and Department of Physiology & Pathophysiology University of Manitoba, Winnipeg, Canada.
Elena BignamiAnesthesiology, Critical Care and Pain Medicine Division, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Fumio SakamakiDepartment of Respiratory Medicine, Tokai University Hachioji Hospital, Tokai University School of Medicine, Tokyo, Japan.
Giandomenico RovielloDepartment of Health Sciences, University of Florence, Florence, Italy.
Hirokazu TaniguchiClinical Oncology Center, Nagasaki University Hospital, Nagasaki, Japan.
Kyeongman JeonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lenko SaricDepartment of Anesthesiology, Reanimatology and Intensive Care, University Hospital Split, Split, Croatia.
Miguel Ariza-ProtaDivision of Respiratory Medicine, Interventional Pulmonology Unit, Hospital Universitario Central de Asturias, Oviedo, Spain.
Ninh M La-BeckDepartment of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.
Nobuhiro KanajiDivision of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Satoshi WatanabeDepartment of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Takehito ShukuyaDepartment of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomohiro AkabaDepartment of Respiratory Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Tracy L LeongDepartment of Respiratory Medicine, Austin Hospital, Heidelberg, Victoria, Australia.
Wolfgang GesierichDepartment of Pulmonology, Asklepios Lung Clinic Gauting, Center for Respiratory Medicine and Thoracic Surgery, Gauting, Germany.
Yasuhiko KogaDepartment of Respiratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yoshinori TaninoDepartment of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
Yuji UeharaDepartment of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
Shiyue LiState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Rongchang ChenShenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital, Shenzhen, China.
Chengzhi ZhouState Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although advancements in cancer therapies have substantially improved the survival of cancer patients, these treatments may also result in acute or chronic lung injury. Cancer treatment-related lung injury (CTLI) presents with a diverse array of clinical manifestations and can involve multiple sites. Due to the lack of specific diagnostic protocols, CTLI can deteriorate rapidly and may be life-threatening if not promptly addressed. Unfortunately, there is no universally accepted consensus document on the diagnosis and management of CTLI. Methods: A multidisciplinary panel comprising experts from respiratory and critical care medicine, oncology, radiation oncology, thoracic surgery, radiology, pathology, infectious diseases, pharmacy, and rehabilitation medicine participated in this consensus development. Through a systematic literature review and detailed panel discussions, the team formulated nine key recommendations. Results: This consensus document addresses the concept, epidemiology, pathogenesis, risk factors, diagnostic approach, evaluation workflow, management strategies, differential diagnosis, type-specific management and clinical staging of CTLI. Emphasis is placed on raising awareness among clinicians and therapeutic practices through comprehensive guidelines. Conclusions: The consensus provides a detailed diagnostic protocol for CTLI and introduces a structured management framework based on grading, typing, and staging. It highlights the critical role of multidisciplinary team (MDT) collaboration and emphasizes the need for individualized, whole-process patient care strategies to optimize clinical outcomes.

Indexed as

anti-tumor therapyCancerdiagnosislung injurytreatment

Identifiers

PMID40400937
PMCPMC12090108

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