Evidence map›Paper›PMID 40400895›Full record

ArticleCureus2025

Keratoacanthoma in a Patient With Skin of Color.

William Stansbury, Micah Pippin, Vincent Pham, Ashley Flowers

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William StansburyFamily Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.
Micah PippinFamily Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.
Vincent PhamFamily Medicine, Tulane University School of Medicine, New Orleans, USA.
Ashley FlowersPathology, Louisiana State University Health Sciences Center, Shreveport, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratoacanthomas are rapidly growing, benign cutaneous neoplasms that can mimic squamous cell carcinoma, presenting diagnostic and management challenges for physicians. The case report investigates a 63-year-old African American female who presented to a family medicine clinic with a one-year history of a progressively enlarging nodule on her right shin. Clinical examination revealed a seven-millimeter dome-shaped, hyperpigmented, well-defined, scaly, rough papule with central umbilication and a keratin plug. Histopathological analysis of an excisional biopsy confirmed the diagnosis of keratoacanthoma with clear margins. Due to the significant overlay in gross appearance and dermoscopic features of keratoacanthomas and malignant squamous cell carcinomas, it is imperative to fully excise similarly presenting lesions and send them for microscopic analysis. Even with histologic examination, keratoacanthomas and squamous cell carcinomas can be challenging to differentiate. Therefore, the priority of contemporary research lies in new methods of distinguishing the two conditions so that the self-limited, benign keratoacanthoma can be managed more conservatively, avoiding invasive removal and associated morbidity. This scholarship is especially pertinent to patients, like the one in this case study, with skin of color who are more likely to experience post-operative complications such as proinflammatory hyperpigmentation, hypertrophic scars, and keloids, but are also at risk of squamous cell carcinoma.

Indexed as

benign skin tumordermatologic neoplasmskeratoacanthomaskin of color dermatologysquamous cell carcinoma of the skin

Identifiers

PMID40400895
PMCPMC12094132

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.