Evidence map›Paper›PMID 40400866›Full record

ArticleCureus2025

Systemic Lupus Erythematosus as a Risk Factor for Encapsulating Peritoneal Sclerosis: A Case Report.

Aabid Mohiuddin, Fawaz Hussain, Leslie Lin, Ahmed Alhaj, Yahya Osman-Malik

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aabid MohiuddinDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, USA.
Fawaz HussainDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, USA.
Leslie LinDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, USA.
Ahmed AlhajDivision of Nephrology, Detroit Medical Center/Wayne State University, Detroit, USA.
Yahya Osman-MalikDivision of Nephrology, Detroit Medical Center/Wayne State University, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encapsulating peritoneal sclerosis (EPS) refers to the insidious formation of a thick fibrous cocoon encasing the intra-abdominal organs and may lead to bowel obstruction. EPS is a known but rare complication of chronic peritoneal dialysis (PD) due to the long-term exposure of glucose degradation products and recurrent peritonitis, promoting inflammatory fibrosis and sclerosis of intra-abdominal structures. However, PD patients with systemic lupus erythematosus (SLE) may be at increased risk of developing EPS due to the concurrent immune-mediated inflammation of the peritoneal serosa. This report describes the case of a young female with SLE and end-stage renal disease (ESRD) due to lupus nephritis who developed EPS after five years of PD. Her clinical course was complicated by septic shock and pneumoperitoneum; exploratory laparotomy revealed diffuse fibrous encapsulation of the liver, transverse colon, and stomach requiring surgical enterolysis. This case highlights the role of SLE as an important risk factor for EPS and underscores the need for preventive measures among this high-risk population of chronic PD patients.

Indexed as

encapsulating peritoneal sclerosisfibrosisperitoneal dialysissurgical enterolysissystemic lupus erythematosus

Identifiers

PMID40400866
PMCPMC12094196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.