ArticleCureus2025
Spinal Epidural Abscess: A Single-Center Retrospective Review of Incidence, Risk Factors, and Management at a Community Hospital.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Ventral Cervical Epidural Abscess Presenting as a Stroke Mimic With Paradoxical Thoracic Sensory Level: Diagnostic Challenges and Multimodal Management.The American journal of case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWhile relatively rare, spinal epidural abscess (SEA) is a neurosurgical pathology that can result in life-altering spinal cord injury if not properly managed or if diagnosis is delayed. The textbook presentation of SEA includes the triad of back pain, fever, and neurologic deficits; however, this classic triad is infrequently seen. Due to the nonspecific nature of each individual symptom, the condition is often misdiagnosed, resulting in delayed management and potentially significant consequences for the patient. This study aims to characterize the incidence, risk factors, and management of patients presenting with SEA at Desert Regional Medical Center (DRMC) to optimize the timely identification and treatment of affected individuals at our California community hospital. MATERIALS AND
methodsWe conducted a single-center retrospective review at DRMC of patients diagnosed with SEA. The data collection period spanned from July 1, 2016, to April 29, 2021, and included a total of 88 patients. For each patient, we extracted data on demographics, risk factors, comorbidities, clinical presentation, diagnostics, management, and discharge disposition. We generated frequency tables for qualitative data and conducted exploratory data analysis for quantitative variables, accompanied by a series of visualizations to illustrate our findings. To assess the suitability of parametric testing for future studies, we created Q-Q plots and performed Shapiro-Wilk and Kolmogorov-Smirnov tests.
resultsOur study population demonstrated a male predominance, with a mean age of 57 years. Among the risk factors and comorbidities evaluated, recent infection, smoking, alcohol use, and diabetes mellitus were the most prevalent. Only 6% (5) of patients presented with the classic triad of back pain, fever, and neurologic deficits. The most common locations of epidural abscesses included the lumbar spine, lumbar plus sacral spine, and thoracic spine. Bacteremia was present in 81% (71) of patients, and biopsy cultures were positive in 77% (68) of those who underwent the procedure. The most common treatment approach was a combination of surgical intervention and antibiotic therapy tailored to culture results.
conclusionsThis study enabled us to characterize the SEA patient population at our institution and compare it to the broader literature, facilitating timely diagnosis and management. Given the condition's tendency to present with nonspecific symptoms and elevated but unremarkable inflammatory markers, this additional data may help reduce diagnostic delays and improve patient outcomes. Beyond its implications for SEA management within the DRMC neurosurgical department, this study contributes to the existing body of literature, supporting improved diagnostic and therapeutic strategies at other institutions as well.
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