ReviewCureus2025
Intervention for the Increase in the Uptake of Pneumococcal Vaccination Among Older Patients: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of pneumococcal vaccination in reducing hospitalization and mortality among the elderly: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2025Pooled it
- Article
- Advanced immunology in aging population: unveiling the complexities of vaccine responsiveness.Frontiers in aging · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pneumococcal infection is a significant cause of morbidity and mortality among older adults, with lasting impacts on daily functioning and frailty. Although pneumococcal vaccination is a proven preventive measure, uptake remains low in many primary care settings. This systematic review examined the effectiveness of interventions designed to increase pneumococcal vaccination uptake among older patients in primary care. A comprehensive literature search was conducted in PubMed, Embase, and Web of Science for studies published between January 1995 and April 2025. Studies eligible for inclusion were randomized controlled trials or quasi-experimental studies targeting individuals aged 65 or older. Out of 166 identified records, five studies met the inclusion criteria. Interventions varied widely, including low-literacy educational brochures, computerized physician reminder systems, mailed feedback, point-of-care flyers, and comprehensive system-level programs. All interventions positively affected vaccination uptake, with absolute increases ranging from 1.9% to 35% compared to controls. Strategies targeting healthcare providers, mainly through reminders and feedback mechanisms, tended to yield higher improvements. Only one study was conducted in Asia, indicating a significant gap in regional evidence. The findings suggest that simple and multicomponent interventions can effectively improve pneumococcal vaccination rates in older adults when implemented through primary care. Greater attention to interdisciplinary collaboration and the use of context-specific strategies is warranted. Further trials, particularly in Asian and resource-limited settings, are needed to inform sustainable, scalable approaches to increasing vaccination coverage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.