ArticleReproductive medicine and biology
Effect of aging on semen and embryonic developmental scores in assisted reproductive technology.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Clinical Implications of Paternal Age in Assisted Reproduction: Integrating Sperm Epigenetic Evidence.Journal of clinical medicine · 2026Review
- Effect of aging on semen and embryonic developmental scores in assisted reproductive technology.Reproductive medicine and biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The effects of female aging on fertility have been extensively studied; however, this is not the case for aging males. Embryonic selection using time-lapse observations is helpful for successful embryo transfer; however, information on the effect of male aging on time-lapse is insufficient. We analyzed the impact of paternal aging on sperm characteristics, embryonic developmental kinetics, embryo evaluation score, and pregnancy outcomes. Methods: We used data from patients treated at our clinic between January 2020 and December 2022. We evaluated the effects of aging in men and women on semen data, in vitro fertilization (IVF) results, developmental kinetics, embryo evaluation scores, and embryo transfer outcomes using a retrospective approach. Results: Male aging adversely affected the semen characteristics. Although female aging had adverse effects on IVF, embryonic developmental kinetics, and embryo transfer outcomes, male aging did not have such a significant impact. Female aging decreased the iDAScore and Gardner criteria, whereas male aging did not affect the iDAScore. Conclusions: Aging in males had a negative effect on semen data. Contrary to the impact of aging on women, aging in men did not have a significant effect on embryo and gestation rates following embryo transfer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.