Evidence map›Paper›PMID 40400707›Full record

ArticleReproductive medicine and biology

Foundational basic animal experiments paved the way for the clinical development of uterus transplantation.

Iori Kisu, Makoto Mihara, Hisako Hara, Yojiro Kato, Yusuke Matoba, Yohei Yamada, Kentaro Matsubara, Hideaki Obara, Nobuhiko Suganuma, Kouji Banno

Abstract readLetter
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Iori KisuDepartment of Obstetrics and Gynecology Keio University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-1143-9855
Makoto MiharaLymphedema Clinic Tokyo Tokyo Japan.
Hisako HaraLymphedema Clinic Tokyo Tokyo Japan.
Yojiro KatoDivision of Gastroenterological & General Surgery, Department of Surgery, School of Medicine Showa University Tokyo Japan.
Yusuke MatobaDepartment of Obstetrics and Gynecology Hiroshima University Hospital Hiroshima Japan.
Yohei YamadaDepartment of Pediatric Surgery Keio University School of Medicine Tokyo Japan.
Kentaro MatsubaraSetagaya Vascular Clinic Tokyo Japan.
Hideaki ObaraDepartment of Surgery Keio University School of Medicine Tokyo Japan.
Nobuhiko SuganumaDepartment of Obstetrics and Gynecology, Bantane Hospital Fujita Health University School of Medicine Nagoya Japan.ORCID https://orcid.org/0009-0007-0694-2014
Kouji BannoCenter of Maternal-Fetal/Neonatal Medicine Hiroshima University Hospital Hiroshima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterus transplantation (UTx) has emerged as a revolutionary treatment for absolute uterine factor infertility, made possible by extensive preclinical research. Animal studies have played a pivotal role in advancing UTx to clinical practice. We highlight Japan's contribution, including non-human primate research and regulatory progress, leading to its anticipated clinical implementation. The expansion of UTx in the Asia-Oceania region underscores its global impact. Further refinements in surgical techniques, optimization of immunosuppressive regimens, and establishment of clear patient eligibility criteria will be crucial for ensuring the long-term success and sustainability of UTx programs worldwide. This letter acknowledges the Swedish team's foundational efforts in establishing UTx as a viable reproductive technology.

Indexed as

animal researchclinical applicationnon‐human primateuterine factor infertilityuterus transplantation

Identifiers

PMID40400707
PMCPMC12093328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.