Evidence map›Paper›PMID 40400657›Full record

ArticleCureus2025

The Effectiveness of Topical Lactic Acid Gel in Episiotomy Wound Healing and Its Impact on Sexual Quality of Life After Childbirth: A Prospective Study.

Dragos Brezeanu, Ana-Maria Brezeanu, Sergiu Chirila, Vlad I Tica

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dragos Brezeanu6th Department, Faculty of Medicine, Ovidius University, Constanta, ROU.
Ana-Maria Brezeanu6th Department, Faculty of Medicine, Ovidius University, Constanta, ROU.
Sergiu Chirila6th Department, Faculty of Medicine, Ovidius University, Constanta, ROU.
Vlad I Tica6th Department, Faculty of Medicine, Ovidius University, Constanta, ROU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe postpartum period is essential for maternal recovery, significantly impacting both physical wound healing and the restoration of sexual function. Optimal episiotomy healing is directly correlated with improved postpartum sexual health, and lactic acid is being explored as a therapeutic agent in wound care due to its antimicrobial and regenerative properties. This study aims to evaluate the efficacy of topical lactic acid (Canesbalance®, Bayer, Leverkusen, Germany) in promoting episiotomy healing and its subsequent influence on postpartum sexual quality. Additionally, it explores how demographic factors, such as educational level, maternal age, and parity, affect postpartum sexual function.

methodsWe conducted a prospective comparative study involving 100 postpartum women divided into two groups: an experimental group treated with topical lactic acid gel applied to the episiotomy site seven days postpartum and a control group undergoing spontaneous wound healing without intervention. Episiotomy healing quality and sexual function were assessed once at 40 days postpartum using a 12-item sexual quality of life questionnaire. This was the only follow-up point in the study, and no additional clinical visits or evaluations were conducted beyond the 40-day postpartum assessment. Statistical analyses included independent t-tests to compare healing scores, ANOVA for evaluating demographic influences on sexual function, and correlation analyses between healing quality and postpartum sexual function scores.

resultsThe lactic acid-treated group demonstrated significantly improved episiotomy healing scores compared to the control group. Educational level significantly influenced postpartum sexual quality, with higher education correlating with improved sexual function. Maternal age and parity did not demonstrate statistically significant effects on postpartum sexual function.

conclusionTopical lactic acid application significantly improves episiotomy wound healing and positively impacts postpartum sexual function. Educational attainment emerged as an important determinant of sexual quality postpartum. These findings advocate for further studies to confirm the long-term benefits and wider clinical applicability of lactic acid in postpartum care.

Indexed as

episiotomylactic acidperineal wound carepuerperiumquality of sexual life

Identifiers

PMID40400657
PMCPMC12093132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.