ReviewFrontiers in medicine2025
Hypersensitivity reactions to iodinated contrast media: potential mechanisms and clinical management.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Negative Predictive Value of Allergologic Work-Up with Iodinated Contrast Media in 'Real-Life' Practice.Journal of clinical medicine · 2026Article
- Comparison of Low-Iodine Concentration Quantification Accuracy and Contrast-To-Noise Ratio Across Three Dual-Energy CT Techniques: A Phantom Study.Journal of medical radiation sciences · 2026Article
- Contrast Media Side Effects and Kounis Syndrome: Timeo Danaos et Dona Ferentes.Balkan medical journal · 2026Review
- Iodinated Contrast Media in Oncologic CT: A Narrative Review of Safety, Risk Stratification, and Practical Considerations.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluation of Presacral Vascular Anatomy Using Contrast-Enhanced 3D-CT for Surgical Planning in Endoscopic Sacrocolpopexy.Diagnostics (Basel, Switzerland) · 2026Article
- US Food and Drug Administration black box warnings: Characteristics of drug classes and adverse effects.The Journal of pharmacology and experimental therapeutics · 2026Article
- Generation of deep learning based virtual contrast-enhanced CT images from noncontrast CT images for target volume delineation in cervical cancer radiotherapy.Frontiers in oncology · 2026Article
- Hyperprolactinemia and Brain Health: Exploring the Gut-Brain Axis and Therapeutic Strategies.Molecular neurobiology · 2025Review
- Seizures as an Initial Manifestation of Severe Anaphylaxis Following Intrathecal Contrast Injection: A Case Report.Case reports in critical care · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iodinated contrast media (ICM) are indispensable in modern imaging, but hypersensitivity reactions (HSRs), ranging from mild urticaria to severe anaphylaxis, remain a significant and evolving clinical challenge. Although advancements in ICM formulations and HSR management, ongoing discussions and uncertainties persist, particularly regarding variable epidemiology, complex mechanisms, and debatable clinical management strategies. This review provides a comprehensive overview and insights into the epidemiology, clinical consequences, potential mechanisms, clinical management, and current controversies associated with HSRs to ICM. Ongoing research is critical, focusing on areas such as monitoring epidemiological trends, uncovering underlying mechanisms, improving risk prediction, and refining preventive, diagnostic, and therapeutic strategies. Overall, as the use of ICM continues to rise, balancing their diagnostic benefits with effective management of HSRs is essential to optimizing patient safety and clinical outcomes.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.