Evidence map›Paper›PMID 40400625›Full record

SynthesisFrontiers in medicine2025

Bibliometric analysis of tumor marker application in gastric cancer diagnosis from 2019 to 2024.

Zhanat Komekbay, Reza Shirazi, Gulnaz Yessultanova, Alisher Garifollin, Anar Tulyayeva, Nurgul Kereyeva, Saule Akhmetova, Abdiraman Kaliev

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhanat KomekbayDepartment of Histology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Reza ShiraziDepartment of Anatomy, School of Biomedical Sciences, Medicine and Health, University of New South Wales, Sydney, NSW, Australia.
Gulnaz YessultanovaDepartment of Histology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Alisher GarifollinDepartment of Histology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Anar TulyayevaDepartment of Oncology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Nurgul KereyevaDepartment of Oncology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Saule AkhmetovaDepartment of Pathological Anatomy and Forensic Medicine, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Abdiraman KalievDepartment of Pathological Anatomy and Forensic Medicine, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer remains a significant global health challenge, ranking fifth worldwide in both incidence and mortality worldwide. Early detection and accurate prognosis are crucial for effective management, yet current diagnostic methods, including tumor markers, often exhibit less sensitivity. This bibliometric analysis investigates trends and key contributions in research on tumor markers for gastric cancer diagnosis from 2019 to 2024. Using Scopus and Web of Science databases, 2,940 articles were analyzed to assess publication trends, prominent authors, institutions, and emerging research themes. Results highlight East Asia, particularly institutions like Fudan University and Nanjing Medical University, as a hub for groundbreaking research. The study identifies key tumor markers and advances in molecular diagnostics, with emphasis on personalized medicine and early detection strategies. Visualization of global collaborations reveals extensive networks driving innovation in this field. While this analysis underscores progress in gastric cancer biomarker research, it also identifies limitations, including language bias and a narrow temporal scope. Future research should prioritize novel biomarkers, integrate advanced technologies like AI, and enhance international cooperation to further improve outcomes for gastric cancer patients.

Indexed as

diagnosisgastric cancerimmunohistochemistryprognosistumor marker

Identifiers

PMID40400625
PMCPMC12092446

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.