Evidence map›Paper›PMID 40400552›Full record

ArticleEnvironment & health (Washington, D.C.)2025

Protective Effects of Octyl Gallate Against Deoxynivalenol-Induced Colon Inflammation: Insights from Proteomic and Metabolomic Analyses.

Chenxin Dongye, Xiangrong Chen, Yanfang Zhao, Huijuan Li, Mohamed F Abdallah, Tianliang Li, Xiangfeng Chen

Abstract read
In one paragraph

Article in Environment & health (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenxin DongyeShandong International Joint Laboratory of Environmental and Biological Science, Qilu University of Technology (Shandong Academy of Science), Jinan, Shandong 250014, China.
Xiangrong ChenShandong International Joint Laboratory of Environmental and Biological Science, Qilu University of Technology (Shandong Academy of Science), Jinan, Shandong 250014, China.
Yanfang ZhaoShandong International Joint Laboratory of Environmental and Biological Science, Qilu University of Technology (Shandong Academy of Science), Jinan, Shandong 250014, China.
Huijuan LiShandong International Joint Laboratory of Environmental and Biological Science, Qilu University of Technology (Shandong Academy of Science), Jinan, Shandong 250014, China.
Mohamed F AbdallahDepartment of Human Biology and Toxicology, Faculty of Medicine, Pharmacy and Biomedical Sciences, University of Mons, Mons 7000, Belgium.ORCID https://orcid.org/0000-0002-3903-6452
Tianliang LiCenter for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Xiangfeng ChenShandong International Joint Laboratory of Environmental and Biological Science, Qilu University of Technology (Shandong Academy of Science), Jinan, Shandong 250014, China.ORCID https://orcid.org/0000-0001-9056-7585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deoxynivalenol (DON) and octyl gallate (OG) are prevalent compounds in the environment and food. DON is frequently detected in cereals such as corn and wheat, while OG is commonly employed as a food additive. As a result, human exposure to these substances is inevitable. Given this, the objective of this experiment was to investigate the impact of co-exposure to DON (10 μg/kg) and OG (10 μg/kg) on intestinal inflammation. The RAW264.7 macrophage cell line was utilized to analyze cytokine levels as well as proteomic and metabolomic changes. In the quantitative real-time PCR experiments, the DON group showed significant difference compared to the control group (*

Identifiers

PMID40400552
PMCPMC12090014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.