ArticleRoyal Society open science2025
Causal relationship between gut microbiota, blood metabolites and autism spectrum disorder: a Mendelian randomization study.
Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Blood Metabolites Mediate the Effects of Gut Microbiota on Diabetic Nephropathy: A Mendelian Randomization Study.International journal of endocrinology · 2026Article
- The Microbiota-Gut-Brain Axis in Autism: Associations, Causal Inference, and Interventions-A Narrative Review.Pathogens (Basel, Switzerland) · 2025Review
- Causal relationship between gut microbiota, blood metabolites and autism spectrum disorder: a Mendelian randomization study.Royal Society open science · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study explored the causal relationships between gut microbiota, blood metabolites and autism spectrum disorder (ASD) in children and assessed whether metabolites mediate the relationship between microbiota and ASD. Using Mendelian randomization (MR), causal links between gut microbiota, blood metabolites and ASD were analysed, alongside reverse MR to examine reverse causality. A two-step MR mediation analysis was used to assess metabolite mediation. The study identified 15 gut microbiota types significantly associated with ASD, with Marinilabiliaceae showing the strongest positive link (odds ratio (OR) = 5.206, 95% confidence interval (CI) = 1.2783-21.2017,
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