Evidence map›Paper›PMID 40400361›Full record

ArticleBehavioral sleep medicine

Mental Health, Substance Use, and Related Factors Associated with Recent Use of Cannabis for Sleep: A Co-Twin Control Study.

Zoë Panchal, Joseph Sakai, Andrea N Goldstein-Piekarski, Jarrod M Ellingson, William Iacono, Robin P Corley, Scott Vrieze, Christian J Hopfer, John K Hewitt, Matt K McGue and 1 more

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioral sleep medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zoë PanchalDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Joseph SakaiDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Andrea N Goldstein-PiekarskiDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Jarrod M EllingsonDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
William IaconoDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Robin P CorleyInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Scott VriezeDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Christian J HopferDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
John K HewittInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Matt K McGueDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
J Megan RossDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Funding

Rocky Mountain Cannabis Research CenterP50DA056408 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Angela Bryan · 2023 to 2026
$14.0M
Development of Psychopathology, Psychobiology, & BehaviorT32MH015442 · NIMH · UNIVERSITY OF COLORADO DENVER · PI JASON R TREGELLAS · 1985 to 2026
$10.2M
The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsR01DA042755 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Jarrod Martin Ellingson, SOO H RHEE · 2017 to 2026
$9.9M
TWIN STUDY OF FEMALE ALCOHOLISMS AND OTHER DISORDERSR01AA009367 · NIAAA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MCGUE, MATTHEW K. · 1992 to 2013
$9.0M
Adolescent drinking and midlife outcomes: A prospective cotwin control studyR37AA009367 · NIAAA · UNIVERSITY OF MINNESOTA · PI MCGUE, MATTHEW K. · 2016 to 2024
$5.4M
Understanding the links between parental and adolescent substance use:complementary natural experiments using the children of twins designR01DA054087 · NIDA · UNIVERSITY OF COLORADO · PI Matthew Charles Keller, SOO H RHEE · 2022 to 2026
$4.9M
Adult Progression of Adolescent Onset Substance Use Disorder in a High Risk SampleR01DA053693 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Christian J Hopfer, Michael Craig Stallings · 2022 to 2026
$3.2M
Effects of High Potency Cannabis Products on Mental Health and Psychosocial FunctioningR01DA057894 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Christian J Hopfer · 2023 to 2026
$2.7M
Mentoring Clinical Investigators in Adolescent-onset Substance Use Disorders ResearchK24DA032555 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J · 2013 to 2022
$1.9M
Changes in cognition and psychiatric disorder symptoms during cannabis abstinence using a novel discordant twin designK23DA054212 · NIDA · UNIVERSITY OF COLORADO DENVER · PI ROSS, JESSICA MEGAN · 2021 to 2025
$1.0M
Pathways for Physician Scientist Training in Psychiatric ResearchR25MH125758 · NIMH · UNIVERSITY OF COLORADO DENVER · PI C. Neill EPPERSON, Susan Kay Mikulich-Gilbertson · 2021 to 2026
$980k
NIAAA NIH HHS R01 AA009367NIAAA NIH HHS R37 AA009367NIDA NIH HHS K23 DA054212NIDA NIH HHS K24 DA032555NIDA NIH HHS P50 DA056408NIDA NIH HHS R01 DA042755NIDA NIH HHS R01 DA053693NIDA NIH HHS R01 DA054087NIDA NIH HHS R01 DA057894NIMH NIH HHS R25 MH125758NIMH NIH HHS T32 MH015442
6 · The paper itself

Abstract

objectivesTo examine: 1) cross-sectional associations between past-month use of cannabis for sleep with mental health, substance use, and related factors in adults and 2) the role of genetic and early environmental factors shared by twins (familial confounds) in explaining significant associations.

methodsIn a population-based sample of adult twins (

resultsRecent use of cannabis for sleep was associated with multiple mental health, substance use, and related factors in phenotypic models. In co-twincontrol models, within-family effects were significant between using cannabis for sleep with more problems from cannabis use, higher cannabis frequency, worse sleep quality, and more frequent use of alcohol and medication for sleep.

conclusionsFamilial confounds may explain many, but not all, associations between recent use of cannabis for sleep and mental health, substance use, and related factors. Longitudinal work is needed to clarify the directionality of associations not explained by familial confounds, and whether they are risks of using cannabis for sleep.

Indexed as

CannabisMarijuana UseMental DisordersMental HealthSleepSleep Wake DisordersSubstance-Related DisordersAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSleep QualityTwins

Identifiers

PMID40400361
PMCPMC12353922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.