Evidence map›Paper›PMID 40400285›Full record

Trial reportJournal of periodontal research2025

Retinol-Augmented PRF Versus PRF Alone in Periodontal Regeneration: A Randomized Clinical Trial.

Abdallah Hassan, Weam Elbattawy, Dalia Sanaa, Alaa Nawwar, Sameh Magdeldin, Maha Mokhtar, Taghreed Khaled Abdelmoneim, Karim Fawzy El-Sayed

Abstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of periodontal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdallah HassanOral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Weam ElbattawyOral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Dalia SanaaOral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Alaa NawwarOral and Maxillofacial Radiology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Sameh MagdeldinProteomics and Metabolomics Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt, Cairo, Egypt.
Maha MokhtarProteomics and Metabolomics Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt, Cairo, Egypt.
Taghreed Khaled AbdelmoneimProteomics and Metabolomics Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt, Cairo, Egypt.
Karim Fawzy El-SayedOral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-6261-3609

Funding

The authors received no specific funding for this work
6 · The paper itself

Abstract

VitA/i-PRF and i-PRF alone improved clinical and radiographic outcomes of M-MIST in periodontal intraosseous defects of patients with stage-III grade B periodontitis. VitA/i-PRF showed a minor, clinically non-significant advantage in defect depth reduction and bone fill at 6 months, with effects diminishing by 9 months in patients with stage-III grade B periodontitis.

Indexed as

Alveolar Bone LossGuided Tissue Regeneration, PeriodontalPeriodontitisVitamin AAdultBone RegenerationFemaleHumansMaleMiddle AgedTreatment OutcomeVitamin Aminimally invasive surgeryperiodontalperiodontitisplatelet‐rich fibrinpocketretinolvitamin A

Identifiers

PMID40400285
PMCPMC12476082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.