ArticleAnimal bioscience2025
Effects of dietary medium-chain fatty acid supplementation levels on growth performance, blood parameters, fecal score and metabolites in nursery pigs.
Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Optimal ratio of laurate and butyrate from glyceride forms improves nutrient digestibility and health in weaned piglets.Animal bioscience · 2026Article
- Effects of dietary medium-chain fatty acid supplementation levels on growth performance, fecal score, energy, antioxidant, inflammatory status, and fecal metabolites of nursery pigs fed high-protein diets.Journal of animal science · 2026Article
- Effects of medium-chain fatty acid supplementation levels in early nursery diets on growth performance, fecal score, gut permeability, energy status, and apparent total tract digestibility of weaning pigs.Translational animal science · 2025Article
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Authors and funding
6 authors.
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Abstract
objectiveThis study evaluated the effects of increasing medium-chain fatty acid (MCFA) supplementation levels on growth performance, blood parameters, fecal score, and metabolites in nursery pigs.
methodsA total of 100 newly weaned pigs (initial body weight: 6.68±0.97 kg) were allotted to 5 treatments in 5 replicates, with 4 pigs per pen for a 28-d feeding trial. Treatments were MCFA supplementation levels at 0.0%, 0.4%, 0.8%, 1.2%, and 1.6%. The 2% soybean oil in the basal diet was replaced with MCFA (a 50:50 blend of free caproic and caprylic acids) on a weight-to-weight basis.
resultsIncreasing MCFA levels tended to linearly increase the final body weight (p = 0.06) and average daily gain in the overall period (p = 0.06), with no difference in overall average daily feed intake. The gain-to-feed ratio increased linearly in d 7-14 (p = 0.06, tendency) and 14-21 postweaning (p<0.05). Fecal score linearly decreased in d 0-7, 7-14, and 14-21 (p<0.05) postweaning, resulting in a linear reduction in the overall period (p<0.05). Plasma malondialdehyde levels at d 28 postweaning showed a quadratic decrease with increasing MCFA levels with the lowest value at 0.8% (p<0.05). Plasma free fatty acid levels at d 14 postweaning linearly decreased with increasing MCFA levels (p<0.05). Fecal total short-chain fatty acid (SCFA) concentrations tended to be lower (p = 0.09, tendency) in the MCFA treatments (0.4%-1.6%) than the control treatment (0.0%). There were no differences in plasma superoxide dismutase activity and fecal ammonia concentrations among dietary treatments.
conclusionIncreasing MCFA supplementation levels up to 1.6% could improve growth rate, feed efficiency, and fecal consistency without affecting feed intake and have the potential to reduce oxidative stress and free fatty acid levels in weaning pigs, while fecal SCFA concentrations could be slightly reduced by MCFA supplementation.
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