Evidence map›Paper›PMID 40400105›Full record

Observational studyBJOG : an international journal of obstetrics and gynaecology2026

Fetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study.

Andrea Dall'Asta, Chiara Melito, Beatrice Valentini, Mariagrazia Capurso, Maria Teresa Baffa, Olga Patey, Basky Thilaganathan, Tullio Ghi

Abstract readObservational Study
In one paragraph

Observational study in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study.BJOG : an international journal of obstetrics and gynaecology · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea Dall'AstaDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.ORCID https://orcid.org/0000-0001-7201-0206
Chiara MelitoDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.ORCID https://orcid.org/0000-0002-7347-021X
Beatrice ValentiniDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.
Mariagrazia CapursoDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.
Maria Teresa BaffaDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.
Olga PateyFetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, University of London, London, UK.ORCID https://orcid.org/0000-0001-8008-5144
Basky ThilaganathanFetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, University of London, London, UK.ORCID https://orcid.org/0000-0002-5531-4301
Tullio GhiDepartment of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess fetal myocardial deformation in normo-oxygenated foetuses in early labour and its relationship with intrapartum outcomes.

designSingle centre prospective study.

settingReferral tertiary maternity unit. POPULATION: Uncomplicated singleton term pregnancies in early labour.

methodsTwo-dimensional (2D) ultrasound clips of the 4-chamber view of the fetal heart were collected in labour and sent to TomTec software for the offline speckle tracking echocardiography analysis. The left (LV) and right ventricular (RV) myocardial (MyoGLS) and endocardial longitudinal (EndoGLS) strain were evaluated.

main outcome measuresOperative delivery including caesarean or assisted vaginal birth due to suspected intrapartum fetal compromise (IFC) as defined by standard CTG criteria.

resultsIn total, 208 cases were included. Operative delivery due to suspected IFC was recorded in 20 (9.6%) cases and was associated with higher LV ejection fraction (EF) (47.4 + 8.2 vs. 40.9 + 12.9%, p = 0.03) and increased RV MyoGLS (-15.9 + 4.0 vs. -12.5 + 4.3%, p < 0.01) and RV EndoGLS (-17.7 + 4.4 vs. -14.3 + 4.7%, p < 0.01) compared to cases not having operative delivery due to suspected IFC. Maternal age (OR 1.138, 95% CI [1.010-1.281], p = 0.03), baseline fetal heart rate at acquisition (OR 1.068, 95% CI [1.007-1.134], p = 0.03) and RV MyoGLS (OR 0.575, 95% CI [0.366-0.903], p = 0.02) were independently associated with the primary outcome.

conclusionsIncreased right ventricular myocardial deformation is associated with operative delivery due to suspected IFC, suggesting an early cardiac response to labour-related hypoxia.

Indexed as

Fetal DistressFetal HeartAdultCesarean SectionDelivery, ObstetricEchocardiographyFemaleHumansLabor, ObstetricLabor Stage, FirstPregnancyPregnancy OutcomeProspective StudiesUltrasonography, Prenatalfetal cardiac functionintrapartum fetal distresslabourobstetric interventionsplacental insufficiency

Identifiers

PMID40400105
PMCPMC13143557

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.