Evidence map›Paper›PMID 40400057›Full record

ReviewPhotochemistry and photobiology

Grape constituents for protection against photodamage to skin.

Yuri Kwon, Rubina Shafi, Allen Oak, Mohammad Athar, Andrzej Slominski, Craig A Elmets

Abstract readReview
In one paragraph

Review in Photochemistry and photobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuri KwonDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Rubina ShafiDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Allen OakDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mohammad AtharDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-5829-7992
Andrzej SlominskiDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-8963-3995
Craig A ElmetsDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-7131-4697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous overexposure to ultraviolet radiation has a variety of deleterious effects. The extent to which dietary factors are effective at moderating UV damage is a significant issue. Grapes contain phytochemicals that protect against excessive UV damage. Components of grapes, in particular resveratrol, proanthocyanidins, and cyanidin-3-glucoside, are receiving considerable attention for their photoprotective actions because of their lack of toxicity, abundance, and low cost. Resveratrol and proanthocyanidins are potent antioxidants that interfere with signal transduction and immunosuppressive pathways activated by UV radiation, which are responsible for its harmful effects. Studies in humans provide a rationale for their further development as a novel method of photoprotection.

Indexed as

SkinUltraviolet RaysVitisAnimalsAnthocyaninsAntioxidantsGlucosidesHumansProanthocyanidinsResveratrolStilbenesAnthocyaninsAntioxidantsGlucosidesProanthocyanidinsResveratrolStilbeneschemopreventionpolyphenolsresveratrolskin cancerultraviolet radiation

Identifiers

PMID40400057
PMCPMC12621086

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.