Evidence map›Paper›PMID 40400046›Full record

ArticleImplementation science communications2025

Planning for scale: analysis of adaptations and contextual factors influencing scale-up of the QUALI-DEC intervention to optimize caesarean section use.

Soha El-Halabi, Claudia Hanson, Alexandre Dumont, Amanda Cleeve, Helle Mölsted Alvesson, Charles Kaboré, Guillermo Carroli, Pisake Lumbiganon, Quoc Nhu Hung Mac, Ana Pilar Betran and 3 more

Abstract read
In one paragraph

Article in Implementation science communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Soha El-HalabiDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden. soha.el.halabi@ki.se.ORCID http://orcid.org/0000-0001-7107-9367
Claudia HansonDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Alexandre DumontUniversité Paris Cité, IRD, Inserm, Ceped, 75006, Paris, France.
Amanda CleeveDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Helle Mölsted AlvessonDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Charles KaboréInstitut de Recherche en Sciences de La Santé (IRSS), Ouagadougou, Burkina Faso.
Guillermo CarroliCentro Rosarino de Estudios Perinatales, Rosario, Argentina.
Pisake LumbiganonDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Quoc Nhu Hung MacPham Ngoc Thach University, Ho Chi Minh City, Vietnam.
Ana Pilar BetranDepartment of Sexual and Reproductive Health and Research, UNDP/UNFPA/UNICEF/WHO/World Bank Special Program of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.
Kristi Sidney AnnerstedtDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Meghan A BohrenGender and Women's Health, Nossal Institute for Global Health, School of Population and Global Health, University of Melbourne, Melbourne, Australia.
Karen ZamboniDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Funding

Horizon 2020 847567World Health Organization 001
6 · The paper itself

Abstract

backgroundResearchers are encouraged to plan for scale through purposeful and guided assessment of scalability of an intervention. This study analysed factors potentially influencing scale-up and synthesised early adaptations of the QUALI-DEC intervention aiming to improve the appropriate use of caesarean section. The intervention consists of opinion leader engagement, audit and feedback for caesarean section, a tool to help women make an informed decision on the mode of birth, and labour companionship.

methodsWe conducted a framework analysis, which was guided by the scalability assessment framework by Zamboni et al., a 34-item checklist with a three-point scale. We used data from the formative research including a document review, hospital readiness assessment and qualitative interviews conducted between March 2019 and May 2020 in 32 facilities across Argentina, Burkina Faso, Thailand, and Viet Nam. Data were deductively coded based on the four dimensions of the scalability framework. Our findings were validated with implementing partners across countries.

resultsWe identified the perceived relevance of the intervention by women and providers and the presence of relevant key clinical guidelines as factors that may ease scalability of QUALI-DEC. Labour companionship and the decision-analysis tool were perceived as harder to scale-up and requiring additional changes to existing healthcare structures. Most of the study facilities reported high workload and time constraints as implementation barriers. Thailand was the only country with a national policy to reduce unnecessary caesarean sections. Legal disputes were common and followed a structured process in Thailand and Argentina, which may support preference of caesarean section due to fear of litigation. Early adaptations included development, revision and translation of educational material, monetary compensation of opinion leaders and reaching consensus on clinical guidelines to be used across hospitals, most of which are deemed conducive to scale up.

conclusionsPlanning for scale-up is a key feature of the QUALI-DEC intervention. Scale-up may not be guaranteed at this point of the intervention since effectiveness and cost-effectiveness are not demonstrated yet. However, the investment in studying scale-up opportunities is a core contribution to implementation research. This exercise informed implementation and scale-up strategies of the QUALI-DEC intervention.

Indexed as

AdaptationsAssessmentCaesarean sectionFormative researchImplementation researchInterventionMaternal healthScalabilityScale-up

Identifiers

PMID40400046
PMCPMC12093684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.