Evidence map›Paper›PMID 40399964›Full record

ReviewJournal of orthopaedic surgery and research2025

Diagnostic imaging confusion in infectious spondylitis.

Zhihao Xu, Weijian Zhu, Sirui Zhou, Zhiying Yang, Liqiao Xiang, Jinming Zhang, Kangshou Liu

Abstract readReview
In one paragraph

Review in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhihao Xu *Department of Hepatobiliary Surgery, Huaqiao Hospital, Jinan University, Guangzhou, 510630, China.
Weijian Zhu *Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Street, Wuhan, Hubei, 430030, P.R. China.
Sirui ZhouDepartment of Respiration, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430077, China.
Zhiying YangDepartment of Radiology, Zhongshan Hospital of Dalian Medical University, Dalian, 116001, China.
Liqiao XiangQichun Shunkang Nephrology Hospital, Qichun Avenue 127, Huanggang City, 435300, China.
Jinming ZhangDepartment of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Street, Wuhan, Hubei, 430030, P.R. China. zhangjinming1988@163.com.
Kangshou LiuDepartment of Hepatobiliary Surgery, Huaqiao Hospital, Jinan University, Guangzhou, 510630, China. lks1004@jnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfectious spondylitis is a rare but increasingly recognized condition involving infectious lesions of the spine. It can affect patients of all ages and is typically caused by bacterial, fungal, or other pathogens. The infection commonly targets the vertebral bodies and intervertebral discs. Early symptoms of infectious spondylitis are often nonspecific, making it challenging to differentiate from other spinal disorders such as tumors, degenerative diseases, or other types of infections. As the condition can progress rapidly, early diagnosis and intervention are crucial to improving patient outcomes. MAIN BODY: Imaging plays a critical role in the early diagnosis of infectious spondylitis. Magnetic resonance imaging is considered the gold standard due to its superior ability to visualize soft tissue structures and assess the extent of infection. CT imaging and nuclear medicine scans also provide valuable information in certain clinical scenarios, particularly for evaluating bony involvement and detecting occult infection. However, imaging findings in infectious spondylitis can overlap with those of other spinal conditions, making differential diagnosis essential for accurate identification. This study explores the advantages and limitations of different imaging modalities in diagnosing infectious spondylitis, focusing on their ability to suggest the possible etiology, determine the severity of the disease, and guide treatment decisions. Additionally, the relationship between imaging characteristics and clinical symptoms is examined to offer clinicians a systematic approach to improve diagnostic accuracy.

conclusionEarly and accurate diagnosis of infectious spondylitis is critical for preventing long-term complications. Imaging techniques, especially MRI, are invaluable tools for clinicians in identifying this condition, assessing its extent, and guiding treatment. Improved understanding of the imaging features associated with infectious spondylitis is essential for more accurate diagnosis and treatment planning.

Indexed as

SpondylitisDiagnosis, DifferentialHumansMagnetic Resonance ImagingSpineTomography, X-Ray ComputedAnkylosing spondylitisImaging characteristicsInfectious spondylitisModic changes type 1SAPHO syndromeSpinal neuroarthropathySpinal tumorsVertebral hemangiomas

Identifiers

PMID40399964
PMCPMC12096627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.