Evidence map›Paper›PMID 40399940›Full record

ArticleMilitary Medical Research2025

Stem cell-derived co-grafts contribute to retinal reconstruction and visual functional improvement in a laser damaged rat model.

Deepthi S Rajendran Nair, Magdalene J Seiler, Juan Carlos Martinez-Camarillo, Yuntian Xue, Ruchi Sharma, Kapil Bharti, Mark S Humayun, Biju B Thomas

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Military Medical Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Deepthi S Rajendran NairDepartment of Ophthalmology, USC Roski Eye Institute, University of Southern California, Los Angeles, CA, 91030, USA.
Magdalene J SeilerDepartments of Physical Medicine and Rehabilitation, Ophthalmology, Anatomy, and Neurobiology, University of California, Irvine, Irvine, CA, 92697, USA.
Juan Carlos Martinez-CamarilloDepartment of Ophthalmology, USC Roski Eye Institute, University of Southern California, Los Angeles, CA, 91030, USA.
Yuntian XueStem Cell Research Center, University of California, Irvine, Irvine, CA, 92697, USA.
Ruchi SharmaUnit on Ocular and Stem Cell Translational Research, National Eye Institute, NIH, Bethesda, MD, 20892, USA.
Kapil BhartiUnit on Ocular and Stem Cell Translational Research, National Eye Institute, NIH, Bethesda, MD, 20892, USA.
Mark S HumayunDepartment of Ophthalmology, USC Roski Eye Institute, University of Southern California, Los Angeles, CA, 91030, USA.
Biju B ThomasDepartment of Ophthalmology, USC Roski Eye Institute, University of Southern California, Los Angeles, CA, 91030, USA. biju.thomas@med.usc.edu.ORCID http://orcid.org/0000-0001-8851-5241

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
Integration and functionality of retinal organoid transplantsR01EY031834 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEILER, MAGDALENE J · 2021 to 2025
$3.0M
VRC: A Stem Cell-Based Treatment Strategy for Laser-Induced Permanent Retinal DamagesR01EY031144 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, BIJU BLAVADY · 2019 to 2021
$751k
California Institute of Regenerative Medicine DISC1-09912National Institute of Health EY031144National Institute of Health R01 EY031834-01A1NEI NIH HHS EY-017337NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY031144NEI NIH HHS R01 EY031834
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Co-graftRetina laser damageRetinal degenerative diseaseRetinal organoidsRetinal pigment epitheliumRetinal transplantationStem cell-based therapy

Identifiers

PMID40399940
PMCPMC12093716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.