Evidence map›Paper›PMID 40399907›Full record

ArticleHarm reduction journal2025

Dispensing hope: leveraging distribution boxes to enhance low-barrier access to naloxone in healthcare settings.

Nycole Kothe, Angela Gray, Sarah Guthrie, Michael Londner

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nycole KotheWVU Medicine Berkeley Medical Center, 2500 Hospital Drive, Martinsburg, WV, 25401, USA. Nycole.kothe1@wvumedicine.org.
Angela GrayWVU Medicine Berkeley Medical Center, 2500 Hospital Drive, Martinsburg, WV, 25401, USA.
Sarah GuthrieWVU Medicine Berkeley Medical Center, 2500 Hospital Drive, Martinsburg, WV, 25401, USA.
Michael LondnerWVU Medicine Berkeley Medical Center, 2500 Hospital Drive, Martinsburg, WV, 25401, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWest Virginia, often regarded as the epicenter of the opioid epidemic, has consistently recorded the nation's highest rates of opioid overdose deaths. The Eastern Panhandle, which includes Berkeley, Morgan, and Jefferson counties, mirrors this trend, with Berkeley County's overdose death rate in 2020 exceeding triple the national average. Recent data, however, indicates a promising 37% decrease in overdose deaths in Berkeley County over a 12-month period ending August 2024, and a statewide decrease of 27.9%. This decline is suspected to be attributed to enhanced access to naloxone and medications for opioid use disorder, supported by community collaboration. Despite these gains, barriers persist for at-risk populations, necessitating strategies such as over-the-counter naloxone availability.

methodsThe implementation of naloxone distribution boxes in healthcare settings, initiated in Berkeley Medical Center's emergency department, marks a significant advancement. These boxes, accessible at all times and stocked with OTC (over the counter) naloxone kits, were placed in visible areas of the building vestibule to increase community access to naloxone.

resultsOver a six-month period, these boxes distributed 2,383 naloxone kits, significantly surpassing physician-ordered distributions of 17 kits over the same period.

conclusionDistribution boxes allowed for delivery of large quantities of naloxone compared to the physician-ordered distributions. Future efforts aim to expand naloxone availability in community settings to sustain and further reduce overdose fatalities.

Indexed as

Drug OverdoseHealth Services AccessibilityNaloxoneNarcotic AntagonistsOpiate OverdoseOpioid-Related DisordersEmergency Service, HospitalHumansWest VirginiaNaloxoneNarcotic AntagonistsDistributionHarm reductionNaloxoneOpioidOverdoseSubstance use disorder

Identifiers

PMID40399907
PMCPMC12096720

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.