ArticleBMC oral health2025
Influence of local denture-related factors on the inflammatory marker levels in patients with denture stomatitis.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- [Chlorhexidine and Polident Induce the Formation ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Denture hygiene knowledge, cleaning practices, and denture stomatitis among primary care patients in Alkharj, Saudi Arabia: compliance predictors, barriers and educational preferences: a cross-sectional study.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMany denture-related factors have been identified as risk factors for DS, including trauma, nighttime denture wearing, insufficient oral and denture hygiene. The aim of this research was to examine the effects of local denture factors in the oral mucosa and saliva content that occurred after the DS onset. MATERIALS AND
methodsThe study sample comprised 150 adult partial or total denture wearers, 100 of whom were diagnosed with DS, and the remaining 50 had a healthy mucous membrane despite having prosthetic restorations and served as controls. Participants' saliva was tested for the presence of salivary cytokines (IL-1β, TNF-α, and MMP-9) as indicators of inflammation and damage to the oral mucosa.
resultsThe obtained findings confirmed that local denture-related factors have a major influence on the DS occurrence. Moreover, levels of IL-1β, TNF-α, and MMP-9 inflammatory biomarkers were statistically significantly increased in the DS group.
conclusionA significant DS frequency was noted in denture-wearing patients in whom a large number of local denture factors was present. As inflammation is more prevalent among denture wearers than in general population, regular examinations are advised to facilitate an early diagnosis and implement adequate therapy, with a focus on inflammation and DS prevention. CLINICAL RELEVANCE: (1) a greater number of exclusively denture factors can damage the oral mucosa; (2) development of inflammation as a basis for denture stomatitis; (3) increase in the concentration of salivary biomarkers of inflammation; (4) indicates the need for further research regarding the key contributors to the development of DS. CLINICAL TRIAL NUMBER: Not applicable.'
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