SynthesisBMC psychiatry2025
Non-adherence level of pharmacotherapy and its predictors among mental disorders in a resource-limited life trajectories: a systematic review and meta-analysis.
Synthesis in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Ethnopharmacological Use of Mescaline for Psychiatric Disorders: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Effectiveness of the Systems Analysis and Improvement Approach to optimise outpatient mental, neurological, and substance-use disorder treatment cascades in Mozambique: a cluster-randomised trial.The lancet. Psychiatry · 2026Trial
- Importance of providing pharmaceutical care for patients using psychotropic medicines in community pharmacy.Frontiers in public health · 2025Trial
- Integrated Psychological-Behavioral Predictive Model Using Explainable Machine Learning.Healthcare (Basel, Switzerland) · 2026Article
- Analysis of medication adherence and its influencing factors in outpatients with mental disorders: a mixed study in eastern of China.Scientific reports · 2026Article
- Real-world data on uptake and use of digital mental health interventions among waitlisted patients with various mental disorders.Internet interventions · 2026Article
- Arabic validation of the VAGUS insight into psychosis scale among Lebanese patients with schizophrenia.Scientific reports · 2026Article
- Patterns of antidepressant treatment changes among adults with major depressive disorder in Northwest Ethiopia: a hospital-based cross-sectional study.Therapeutic advances in psychopharmacology · 2026Article
- Psychometric properties of the unifactorial and bifactorial models of the Morisky medication adherence scale in Ecuadorians with neuropsychiatric disorders.Frontiers in psychology · 2026Article
- Efficacy of paliperidone palmitate once-monthly (PP1M) in improving social functioning and reducing caregiver burden in patients with schizophrenia: a six-month follow-up study.BMC psychiatry · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite being crucial in ensuring the best treatment outcomes, adherence status is frequently overlooked in comprehensive chronic care. Thus, the present study critically evaluates, integrates, and summarizes psychotropic medication non-adherence and its determinants among patients with mental disorders in a resource limited life trajectories to inform policy and future research.
methodSystematic review and meta-analysis following the Cochrane handbook for systematic reviews of interventions and Preferred Reporting Items for Systematic review and Meta-analysis (PRISMA) statement was conducted. PubMed (Medline), CINAHL, PsychINFO, EMBASE, and Google Scholar databases were comprehensively searched to retrieve published and grey literature from index inception to October 2024. Observational original studies focused on the magnitude of psychotropic treatment non-adherence and its predictors were eligible for inclusion. Risk-of-bias was assessed using Joanna Briggs Institute (JBI) criteria. Protocol was pre-registered at PROSPERO with a reference number of CRD42024578766.
resultsTwenty-three studies (n = 23, 359) were included, 22 of them in the quantitative analysis. The pooled prevalence of non-adherence was 46% (95% CI: 40%-52%, I
conclusionAltogether, we discovered that psychotropic treatment non-adherence among patients with psychiatric disorders was quite common. This analysis may serve as a high-grade ore for policymakers, though it must be interpreted with caution due to significant heterogeneity. Notwithstanding stringent methodology, depending on cross-sectional studies limits its clinical guidance.
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