ArticleCardiovascular intervention and therapeutics2025
Association between myocardial bridge and upstream plaque morphology in patients with acute coronary syndrome.
Article in Cardiovascular intervention and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial bridging (MB), characterized by systolic coronary artery compression, alters coronary flow and may influence upstream atherosclerotic plaque morphology. We aimed to investigate the relationship between MB and morphological features of upstream culprit plaques in patients with acute coronary syndrome (ACS). We retrospectively analyzed 370 ACS patients who underwent optical coherence tomography (OCT)-guided PCI for a de novo culprit lesion in the proximal left anterior descending artery (LAD). OCT images identified plaque rupture (PR), classifying lesions into PR and intact fibrous cap (IFC) groups. The IFC group was further divided based on the presence of lipid-rich plaque (LRP), defined as a plaque with a maximum lipid angle > 90°. This study included 370 ACS patients (mean age 65.2 ± 12.3 years, 82.4% male). Angiographic evidence of MB was present in 8.6% (32/370) of patients prior to PCI and increased to 17.0% (63/370) post-PCI; all MBs identified pre-PCI were also observed post-PCI. OCT identified 213 lesions with plaque rupture and 157 lesions with IFC (of which 83 exhibited underlying LRP and 74 did not). The prevalence of post-PCI angiographically detected MB differed significantly among the OCT-defined morphological groups: 11.3% (24/213) in the PR group, 18.1% (15/83) in the IFC-LRP group, and 32.4% (24/74) in the IFC-non-LRP group (P < 0.01). No periprocedural myocardial injury occurred in the IFC-non-LRP group. In patients with ACS, the presence of MB was significantly associated with a lower likelihood of plaque rupture and LRP in the upstream culprit lesion as assessed by OCT.
Indexed as
Identifiers
40399724What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.