ArticleNature2025
Sequence diversity lost in early pregnancy.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Whole-genome discovery of pathogenic snRNA variants and efficient extended-exome screening.iScience · 2026Article
- Decoding DNA metabolism and its clinical relevance through the lens of high-throughput sequencing assays.Medical review (2021) · 2026Review
- Miscarriage Tissue Research: Still in Its Infancy.Life (Basel, Switzerland) · 2026Review
- Clinical and morphological correlates of embryonic mosaicism: a retrospective cohort study of 10,469 blastocysts in PGT-A cycles.Frontiers in endocrinology · 2026Article
- Anaysis of the association between chromosomal abnormalities in early missed abortion embryos and maternal age and AMH levels based on CNV-Seq.BMC pregnancy and childbirth · 2025Article
- Monogenic Findings in Early Pregnancy Loss: Whole-Exome Sequencing Study of Euploid Products of Conception.Balkan journal of medical genetics : BJMG · 2025Article
- Statistical methods to disentangle genetic effects influencing infertility and early fetal viability with a genome-wide application.PLoS genetics · 2025Article
- Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans.American journal of human genetics · 2025Article
- Immunological Factors in Recurrent Pregnancy Loss: Mechanisms, Controversies, and Emerging Therapies.Biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors.
Gudny A Arnadottir *deCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0001-6571-423X
Hakon Jonsson *deCODE genetics/Amgen, Reykjavik, Iceland. hakon.jonsson@decode.is.ORCID 0000-0001-6197-494X
Tanja Schlaikjær Hartwig *Department of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Jennifer R Gruhn *DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-4093-142X
Peter Loof MøllerDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-1405-5136
Arnaldur GylfasondeCODE genetics/Amgen, Reykjavik, Iceland.
David WestergaardDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0003-0128-8432
Andrew Chi-Ho ChanDNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Asmundur OddssondeCODE genetics/Amgen, Reykjavik, Iceland.
Lilja StefansdottirdeCODE genetics/Amgen, Reykjavik, Iceland.
Louise le RouxdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-9491-9653
Valgerdur SteinthorsdottirdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0003-1846-6274
Kristjan H Swerford MooredeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-9579-4362
Sigurgeir OlafssondeCODE genetics/Amgen, Reykjavik, Iceland.
Pall I OlasondeCODE genetics/Amgen, Reykjavik, Iceland.
Hannes P EggertssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-1674-9978
Gísli H HalldórssondeCODE genetics/Amgen, Reykjavik, Iceland.
G Bragi WaltersdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-5415-6487
Hreinn StefanssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-9331-6666
Sigurjon A GudjonssondeCODE genetics/Amgen, Reykjavik, Iceland.
Gunnar PalssondeCODE genetics/Amgen, Reykjavik, Iceland.
Brynjar O JenssondeCODE genetics/Amgen, Reykjavik, Iceland.
Run FridriksdottirdeCODE genetics/Amgen, Reykjavik, Iceland.
Jesper Friis PetersenDNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
COPL Consortium
Agnar HelgasondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0002-8545-3767
Gudmundur L NorddahldeCODE genetics/Amgen, Reykjavik, Iceland.
Palle Duun RohdeDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-4347-8656
Jona SaemundsdottirdeCODE genetics/Amgen, Reykjavik, Iceland.
Olafur Th MagnussondeCODE genetics/Amgen, Reykjavik, Iceland.
Bjarni V HalldorssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID 0000-0003-0756-0767
Sofie BliddalDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0002-2456-1019
Karina BanasikDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Daniel F GudbjartssondeCODE genetics/Amgen, Reykjavik, Iceland.
Mette NyegaardDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-4973-8543
Patrick SulemdeCODE genetics/Amgen, Reykjavik, Iceland.
Unnur ThorsteinsdottirdeCODE genetics/Amgen, Reykjavik, Iceland.
Eva R HoffmannDNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. eva@sund.ku.dk.ORCID 0000-0002-2588-0652
Henriette Svarre NielsenDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. henriette.svarre.nielsen@regionh.dk.ORCID 0000-0003-2106-8103
Kari StefanssondeCODE genetics/Amgen, Reykjavik, Iceland. kstefans@decode.is.ORCID 0000-0003-1676-864X
Funding
No grant is acknowledged in the PubMed record.
Abstract
Every generation, the human genome is shuffled during meiosis and a single fertilized egg gives rise to all of the cells of the body
Indexed as
Abortion, SpontaneousGenetic VariationGenome, HumanAdultChromosome AberrationsFemaleFetusGenotypeHumansMaleMeiosisMutationOocytesPregnancyWhole Genome Sequencing
Identifiers
What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.