Evidence map›Paper›PMID 40399677›Full record

ArticleNature2025

Molecular basis of positional memory in limb regeneration.

L Otsuki, S A Plattner, Y Taniguchi-Sugiura, F Falcon, E M Tanaka

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Signal control during tissue regeneration in adult animals.Nature reviews. Molecular cell biology · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Static morphogen scaling enables proportional growth in a tissue growth model inspired by axolotl limb regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Hallmarks of regeneration.Cell stem cell · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L OtsukiInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. leo.otsuki@imba.oeaw.ac.at.ORCID 0000-0001-6107-2508
S A PlattnerInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0009-0002-3936-0954
Y Taniguchi-SugiuraInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
F FalconInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
E M TanakaInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. elly.tanaka@imba.oeaw.ac.at.ORCID 0000-0003-4240-2158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The amputation of a salamander limb triggers anterior and posterior connective tissue cells to form distinct signalling centres that together fuel regeneration

Indexed as

Ambystoma mexicanumExtremitiesRegenerationAmputation, SurgicalAnimalsBasic Helix-Loop-Helix ProteinsBody PatterningFeedback, PhysiologicalHedgehog ProteinsSignal TransductionBasic Helix-Loop-Helix ProteinsHedgehog Proteins

Identifiers

PMID40399677
PMCPMC12176643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.