ArticleNature2025
Unravelling cysteine-deficiency-associated rapid weight loss.
Erratum issuedAbstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Moderate iron restriction improves metabolism via epigenetic regulation of GDF15.The Journal of nutritional biochemistry · 2026Article
- Cysteine excess triggers a mitochondrial iron-dependent cell death.Nature metabolism · 2026Article
- ZDHHC17-Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Liver Transplantation in the Era of Metabolic Bariatric Surgery: A Bibliometric Analysis.Obesity surgery · 2026Review
- Preliminary Metabolomic Analysis: Serum Metabolomic Dynamics During Estrus Synchronization in Kazakh Mares.Animals : an open access journal from MDPI · 2026Article
- Blood-based obesity biomarkers and their relevance for disease risk.Nature reviews. Endocrinology · 2026Review
- Methionine restriction and mimetics to ameliorate human aging and disease.Trends in endocrinology and metabolism: TEM · 2026Review
- Functional restructuring of the global soil microbiome under multiple stressors.Nature communications · 2026Article
- Review
- Article
- Renal coenzyme A (CoA) production from VB5 fuels stem cell proliferation and tumor growth.Nature communications · 2026Article
- Endothelial cystathionine-γ-lyase (CTH) regulates body weight and insulin resistance in mice fed a high-fat diet.Redox biology · 2026Article
- Article
- The metabolic signature of excessive endurance exercise-A prospective study in Tour de France cyclists.iScience · 2026Article
- Multi-omics reveals the associations between cecal candidate bacteria and muscle fatty acid composition variations in Daheng and Luning chickens.Frontiers in microbiology · 2026Article
- Hepatic mitochondrial signaling as a systemic hub: inter-organ communication networks in aging and aging-related diseases.Frontiers in cell and developmental biology · 2026Review
- Key dietary amino acids modulating overweight/obesity risk in Chinese children and adolescents: a machine learning analysis of a national survey.Frontiers in nutrition · 2026Article
- Gut microbial metabolites of amino acids in liver diseases.Gut microbes · 2025Review
- Article
- Hepatocyte and adipocyte CDO1-mediated intracellular cysteine catabolism differentially modulates diet-induced obesity and fatty liver in mice.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Commented on by
- Erratum issued
- Update of
Authors and funding
17 authors.
Alan Varghese *Department of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-8052-1428
Ivan Gusarov *Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
Begoña Gamallo-LanaDepartment of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, USA.
Daria DolgonosDepartment of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA.
Yatin MankanDepartment of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA.
Ilya ShamovskyDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
Mydia PhanDepartment of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA.
Rebecca JonesDivision of Advanced Research Technologies, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-5056-9292
Maria Gomez-JenkinsRutgers Cancer Institute, Rutgers University, New Brunswick, NJ, USA.ORCID 0000-0003-3682-9219
Eileen WhiteRutgers Cancer Institute, Rutgers University, New Brunswick, NJ, USA.ORCID 0000-0003-2961-3065
Rui WangDepartment of Biology, York University, Toronto, Ontario, Canada.ORCID 0000-0003-3825-3620
Drew R JonesDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-8732-9818
Thales PapagiannakopoulosDepartment of Pathology, Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.ORCID 0000-0002-2251-1624
Michael E PacoldDepartment of Radiation Oncology and Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-3688-2378
Adam C MarDepartment of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, USA.
Dan R LittmanDepartment of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA. Dan.Littman@med.nyu.edu.ORCID 0000-0002-2850-8688
Evgeny NudlerDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA. Evgeny.Nudler@nyulangone.org.ORCID 0000-0002-8811-3071
Funding
U19 Supplement 2023-FroemkeU19NS107616 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RICHARD W TSIEN · 2018 to 2026
$36.4MDeterminants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiotaR01AI158687 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dan Littman · 2021 to 2026
$3.2MCANCAN-RUTGERSOT2CA278609 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Eileen P. White · 2022 to 2026
$2.6MCellular Adaptations to Nutrient-Limited Metabolic MicroenvironmentsR35GM147119 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Michael Edward Pacold · 2022 to 2026
$2.1MVentana Medical Systems Discovery XTS10OD010584 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHIRIBOGA, LUIS A · 2013 to 2013
$127kSandy Recovery Ventana Medical Systems Discovery XTS10OD018338 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHIRIBOGA, LUIS A · 2014 to 2014
$123kNCI NIH HHS OT2 CA278609NIAID NIH HHS R01 AI158687NIGMS NIH HHS R35 GM147119NIH HHS S10 OD010584NIH HHS S10 OD018338NINDS NIH HHS U19 NS107616
Abstract
Around 40% of the US population and 1 in 6 individuals worldwide have obesity, with the incidence surging globally
Indexed as
CysteineWeight LossAnimalsCitric Acid CycleFemaleFibroblast Growth FactorsGlutathioneGlycolysisMaleMiceMice, Inbred C57BLMitochondriaObesityOxidative StressCysteinefibroblast growth factor 21Fibroblast Growth FactorsGlutathione
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.