Evidence map›Paper›PMID 40399432›Full record

ArticleScientific reports2025

The effect of 2-Deoxy-D-glucose on glycolytic metabolism in acute myeloblastic leukemic ML-1 cells.

Nichlas Vous Christensen, Johanne Haahr Knudsen, Christoffer Laustsen, Lotte Bonde Bertelsen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nichlas Vous ChristensenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.
Johanne Haahr KnudsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.
Christoffer LaustsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.
Lotte Bonde BertelsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark. lotte@clin.au.dk.

Funding

Karen Elise Jensen Fonden 2020
6 · The paper itself

Abstract

Acute myeloblastic leukemia (AML) is one of the most common and life-threatening forms of leukemia. Treatment remains challenging due to its high heterogeneity, drug resistance, and metabolic flexibility. Targeting specific metabolic pathways has emerged as a promising therapeutic approach. The ability to monitor treatment response is crucial for disease management. Here, we utilized hyperpolarized

Indexed as

DeoxyglucoseGlycolysisLeukemia, Myeloid, AcuteCell Line, TumorHumansMagnetic Resonance SpectroscopyDeoxyglucose2-DGAMLGlycolytic metabolismHyperpolarizationNMR

Identifiers

PMID40399432
PMCPMC12095757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.