Evidence map›Paper›PMID 40399358›Full record

ArticleNPJ microgravity2025

Survival strategies of Rhinocladiella similis in perchlorate-rich Mars like environments.

Alef Dos Santos, Júnia Schultz, Felipe Oliveira Souza, Lucas Rodrigues Ribeiro, Thiago Verano Braga, Eduardo Jorge Pilau, Edson Rodrigues-Filho, Alexandre Soares Rosado

Abstract read
In one paragraph

Article in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Enhancing UV-C and perchlorate resistance inFrontiers in microbiology · 2026
    Article
  5. Review
  6. Article
  7. JACS Au · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alef Dos Santos *Department of Chemistry, Federal University of São Carlos, 13565-905, São Carlos, SP, Brazil. alef.dos@umu.se.
Júnia Schultz *Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, 23955, Thuwal, Makkah, Saudi Arabia.
Felipe Oliveira SouzaDepartment of Chemistry, State University of Maringá, 13565-905, Maringá, PR, Brazil.
Lucas Rodrigues RibeiroNational Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), 31270-901, Belo Horizonte, MG, Brazil.
Thiago Verano BragaNational Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), 31270-901, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0002-7083-2588
Eduardo Jorge PilauDepartment of Chemistry, State University of Maringá, 13565-905, Maringá, PR, Brazil.
Edson Rodrigues-FilhoDepartment of Chemistry, Federal University of São Carlos, 13565-905, São Carlos, SP, Brazil.
Alexandre Soares RosadoBiological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, 23955, Thuwal, Makkah, Saudi Arabia. alexandre.rosado@kaust.edu.sa.ORCID http://orcid.org/0000-0001-5135-1394

Funding

King Abdullah University of Science and Technology (KAUST) BAS/1/1096-01-01
6 · The paper itself

Abstract

Studying the survival of terrestrial microorganisms under Martian conditions, particularly in the presence of perchlorates, provides crucial insights for astrobiology. This research investigates the resilience of the extremophile black fungus Rhinocladiella similis to magnesium perchlorate and UV-C radiation. Results show R. similis, known for its tolerance to acidic conditions, exhibits remarkable resistance to UV-C radiation combined with perchlorate, as well as to high concentrations of magnesium perchlorate, surpassing Exophiala sp. strain 15Lv1, a eukaryotic model organism for Mars-like conditions. Growth curve analyses revealed both strains can thrive in perchlorate concentrations mimicking Martian perchlorate-rich environments, with R. similis adapting better to higher concentrations. Morphological and protein production changes were investigated, and mass spectrometry identified perchlorate-induced proteins, advancing molecular understanding of potential microbial life on Mars. These findings advance knowledge of extremophile capabilities, contributing to the search for life beyond Earth and informing the design of future Martian rovers equipped for biosignature detection.

Identifiers

PMID40399358
PMCPMC12095635

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.