Evidence map›Paper›PMID 40399331›Full record

Trial reportScientific reports2025

Rhythm training improves word-reading in children with dyslexia.

Mélanie Descamps, Charline Grossard, Hugues Pellerin, Claire Lechevalier, Jean Xavier, Joana Matos, François Vonthron, Catherine Grosmaitre, Michel Habib, Bruno Falissard and 1 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05154721 (Effect of Music and Rhythm Training Delivered Through a Serious Game on the Reading Skills of Children With a Specific Learning Disorder Impacting Reading, a Multicentric Double-blind and Placebo-controlled Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05154721 nacompletednot on this map

Effect of Music and Rhythm Training Delivered Through a Serious Game on the Reading Skills of Children With a Specific Learning Disorder Impacting Reading, a Multicentric Double-blind and Placebo-controlled Study (Mila-Learn-01)

TypeinterventionalSponsorPoppinsRan2021 to 2023Enrolled151ConditionsLearning Disorder, Specific, Learning Disabilities, Dyslexia, Specific Learning Disorder, With Impairment in ReadingArmsexperimental Group - Mila-Learn, control Group - Mila-Placebo
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mélanie Descamps *bMotion Technologies, Paris, France.
Charline Grossard *Institut des Systemes Intelligents et Robotiques, Sorbonne Université, Paris, France.
Hugues PellerinService de Psychiatrie de l'Enfant et de l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Claire LechevalierPôle Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Spécialisé Henri Laborit, Poitiers, France.
Jean XavierPôle Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Spécialisé Henri Laborit, Poitiers, France.
Joana MatosService de Psychiatrie de l'Enfant et de l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
François VonthronbMotion Technologies, Paris, France.
Catherine GrosmaitreReference Centre of Language and Learning Disorders, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Michel HabibCognitive Neuroscience Laboratory, Neurodys Institute, Aix-Marseille University, UMR 7291, Marseille, France.
Bruno FalissardFaculté de médecine Paris-Saclay, Le Kremlin-Bicêtre, France.
David CohenInstitut des Systemes Intelligents et Robotiques, Sorbonne Université, Paris, France. david.cohen@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific learning disorder with reading deficit (SLD-reading), or dyslexia, is one of the most common neurodevelopmental disorders. Intensive training with reading specialists is recommended, but delayed access to care is common. In this study, we tested an innovative user-friendly and accessible intervention, the medical device Mila-Learn, which is a video game based on cognitive and rhythmic training to improve phonological and reading ability. This randomized placebo-controlled trial (ClinicalTrials.gov NCT05154721) included children aged 7 to 11 y/o with SLD-reading. The children were in 2nd to 5th grade and had been in school for more than 3 years. The exclusion criteria were reading or writing remediation during the past 12 months, previous use of Mila-Learn, and severe chronic illness. The patients, who were all native French speakers, were recruited from throughout France and were randomly assigned to Mila-Learn or a matched-placebo game for an 8-week training. The primary variable was nonword decoding. The secondary variables included phonological skills, 2-min word-reading accuracy and speed, grapheme-to-phoneme conversion skills, and self-esteem. Between September 2021 and April 2023, 151 children were assigned to Mila-Learn (n = 75; male = 36; female = 39) or the placebo (n = 76; male = 42; female = 34). We registered 39 adverse events; only one was due to the protocol and was in the placebo group. We found no differences between the groups in nonword decoding in the intention-to-treat (N = 151; p = 0.39) or per-protocol analysis (N = 93; p = 0.21). However, the per-protocol analysis revealed the superiority of Mila-Learn over the placebo by 5.05 score points (95% CI 0.21; 10.3, p < 0.05) for 2-minute word-reading accuracy and by 5.44 score points (95% CI 0.57; 10.99, p < 0.05) for 2-min word-reading speed. We found no other significant effects. Mila-Learn is safe for children with SLD-reading who might benefit from this medical device.Study registration: ClinicalTrials.gov NCT05154721-13/12/2021.

Indexed as

DyslexiaReadingVideo GamesChildFemaleHumansMale

Identifiers

PMID40399331
PMCPMC12095514

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.