Evidence map›Paper›PMID 40399274›Full record

SynthesisNutrition & diabetes2025

Impact of jujube fruit on serum lipid profile, glycemic index, and liver function: a systematic review and meta-analysis.

Mostafa Ahmadi, Hoda Shirafkan, Seyyed Ali Mozaffarpur, Maedeh Rezghi

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrition & diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Polyphenol-RichNutrients · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mostafa AhmadiStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0002-2386-1255
Hoda ShirafkanSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Seyyed Ali MozaffarpurTraditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Maedeh RezghiTraditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. maedehrezghi@yahoo.com.ORCID 0000-0002-2711-5647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jujube is a widely consumed fruit with a long history in traditional medicine. Numerous studies have explored its potential effects on various health parameters. However, the overall quality of this evidence and the specific impact of jujube on metabolic syndrome remain unclear. This meta-analysis investigates the effect of jujube on body mass index, serum lipid profile, blood sugar levels, and other metabolic factors and blood indicators. The databases Web of Science, Scopus, PubMed, Google Scholar, and SID were searched up to September 2023. Our review included various clinical studies written in English and Persian that focused on the effect of jujube on lipid profiles. In vivo, in vitro, review studies, book chapters, observational studies, and low-quality studies based on critical appraisal tools were excluded from the analysis. A total of seven studies involving 483 participants were included in this review. Jujube significantly reduced BMI and TG, and also markedly decreased FBS in subjects with type 2 diabetes. Furthermore, the results varied significantly based on subgroups defined by dosage, treatment duration, and disease type. Notably, LDL and total cholesterol levels showed a significant decrease within some of these subgroups. However, HDL, AST, and ALT did not have significant changes. The findings suggest that jujube may exert beneficial effects on metabolic diseases, particularly in patients with hyperlipidemia and type 2 diabetes. However, the overall quality of the evidence is limited, and further research is needed to confirm these findings and elucidate the mechanisms underlying jujube's effects. Impact of jujube fruit on serum lipid profile, glycemic index, and liver function: a systematic review and meta-analysis.

Indexed as

Blood GlucoseFruitGlycemic IndexLipidsLiverZiziphusBody Mass IndexDiabetes Mellitus, Type 2HumansPlant ExtractsBlood Glucosejujube extractLipidsPlant Extracts

Identifiers

PMID40399274
PMCPMC12095632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.