Evidence map›Paper›PMID 40399161›Full record

ArticleZeitschrift fur medizinische Physik2025

Advancing risk management in nuclear medicine diagnostic and therapy through incident-driven risk management tools.

Lidia Strigari, David Menichelli, Elisa Lodi Rizzini, Arber Golemi, Gian Mauro Sacchetti, Lucia Leva, Cristina Nanni, Paolo Castelucci, Stefano Fanti, Alessio Giuseppe Morganti and 1 more

Abstract read
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Theranostics in nuclear medicine: the era of precision oncology.Medical oncology (Northwood, London, England) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lidia StrigariDepartment of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: lidia.strigari@aosp.bo.it.
David MenichelliIBA Dosimetry, Bahnhofstraße 5, 90592 Schwarzenbruck, Germany.
Elisa Lodi RizziniRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Arber GolemiNuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Gian Mauro SacchettiNuclear Medicine Department, University Hospital Maggiore della Carità, Novara, Italy.
Lucia LevaNuclear Medicine Department, University Hospital Maggiore della Carità, Novara, Italy.
Cristina NanniNuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Paolo CastelucciNuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Stefano FantiNuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Alessio Giuseppe MorgantiRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Roberta MatheoudMedical Physics Department, University Hospital Maggiore della Carità, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accidental or unintended exposures in nuclear medicine present significant risks, demanding proactive and systematic risk management strategies. This study explores the development and implementation of a novel software tool that integrates Failure Modes and Effects Analysis (FMEA) and Fault Tree Analysis (FTA) into a unified platform tailored for nuclear medicine. The tool addresses the complexities of risk assessment across diagnostic and therapeutic workflows, offering customizable templates and a streamlined process for identifying, prioritizing, and mitigating failure modes. A multicenter study involving nuclear medicine departments of various sizes demonstrated the tool's efficacy in standardizing risk analysis and enhancing interdisciplinary collaboration. Key scenarios, such as errors in radiopharmaceutical preparation and administration, were assessed, with rankings assigned based on a refined Risk Priority Number (RPN) system. The results underscore the transformative potential of combining FMEA and FTA in nuclear medicine, addressing the limitations of standalone methodologies. This approach improves workflow efficiency and ensures a robust framework for patient safety. Future directions include expanding the tool's applications, refining templates, and fostering a proactive culture of risk assessment. These advancements pave the way for safer, more efficient practices in nuclear medicine, benefiting patients and professionals alike.

Indexed as

Nuclear MedicineRisk ManagementHealthcare Failure Mode and Effect AnalysisHumansPatient SafetyRadiopharmaceuticalsRisk AssessmentSoftwareWorkflowRadiopharmaceuticalsExtravasationNuclear medicinePatient risk analysisRadiation safetyRadioembolizationRadioligand therapy

Identifiers

PMID40399161
PMCPMC12766496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.