Evidence map›Paper›PMID 40399101›Full record

ArticleThe Journal of veterinary medical science2025

Life table analysis of feline polycystic kidney disease in Japan.

Takeru Enomoto, Saori Kobayashi, Naomi Ishiguro

Abstract read
In one paragraph

Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Takeru EnomotoLaboratory of Veterinary Small Animal Internal Medicine, Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Iwate, Japan.
Saori KobayashiLaboratory of Veterinary Small Animal Internal Medicine, Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Iwate, Japan.
Naomi IshiguroLaboratory of Veterinary Small Animal Internal Medicine, Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Iwate, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline polycystic kidney disease (PKD) is an inherited renal disorder observed in various breeds. Analyses of life expectancy and distribution of age at death among cats are not well documented. The current study preliminarily assessed life expectancy, cumulative survival rates, and distribution of age at death in cats with PKD by performing a follow-up investigation. This retrospective cohort study was conducted on 300 cats that tested positive for the feline PKD1 variant (c.10063C >A) in Japan. A life table analysis was performed, and a distribution graph of age at death was generated. The life expectancy at birth was approximately 12.7 years, with a 5- and 10-year cumulative survival rates of 95.1% and 61.3%, respectively. Of the 300 cats, 48 (16.0%) progressed to uremia, and 62 (20.7%) died of renal failure and other causes. The median age at death in 62 cats was 8 years, with the first decile being 5 years. The highest number of deaths was at the age of 7 years. The cumulative survival rate began to decline significantly at the age of 6-7 years. This study first performed a survival analysis of feline PKD and provided an important basis for understanding the patterns of overall mortality associated with this genetic disorder. Our findings emphasized the importance of frequent examination at a young age, with consideration of the remarkable decrease in the cumulative survival rate between the ages of 6 and 7 years.

Indexed as

Cat DiseasesPolycystic Kidney DiseasesAnimalsCatsFemaleJapanLife ExpectancyLife TablesMaleRetrospective StudiesTRPP Cation ChannelsTRPP Cation Channelscumulative survival ratefeline polycystic kidney diseasefollow-up investigationlife expectancylife table analysis

Identifiers

PMID40399101
PMCPMC12246562

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.