Evidence map›Paper›PMID 40399091›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Coexistence of IgG4-Related Disease and Renal Anastomosing Hemangioma: A Rare Diagnostic Challenge.

Yo Mizuta, Shunichi Fujita, Masatomo Yamada, Masakatsu Ikeda, Yuka Koide, Sumie Hiramatsu-Asano, Kazuhiro Komi, Hirotake Nishimura, Yoshitaka Morita, Kazuhisa Nakano

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yo MizutaDepartment of Rheumatology, Kawasaki Medical School, Japan.
Shunichi FujitaDepartment of Rheumatology, Kawasaki Medical School, Japan.
Masatomo YamadaDepartment of Rheumatology, Kawasaki Medical School, Japan.
Masakatsu IkedaDepartment of Rheumatology, Kawasaki Medical School, Japan.
Yuka KoideDepartment of Rheumatology, Kawasaki Medical School, Japan.
Sumie Hiramatsu-AsanoDepartment of Rheumatology, Kawasaki Medical School, Japan.
Kazuhiro KomiDepartment of Pathology, Kawasaki Medical School, Japan.
Hirotake NishimuraDepartment of Pathology, Kawasaki Medical School, Japan.
Yoshitaka MoritaDepartment of Rheumatology, Kawasaki Medical School, Japan.
Kazuhisa NakanoDepartment of Rheumatology, Kawasaki Medical School, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgG4-related disease (IgG4RD) is a chronic inflammatory condition that can mimic malignancies. This report describes an 83-year-old male diagnosed with IgG4RD, in whom a left kidney mass was incidentally discovered. Despite glucocorticoid treatment for IgG4RD, the mass did not shrink, and imaging could not exclude malignancy, prompting surgical resection. Pathological examination revealed a rare benign tumor, renal anastomosing hemangioma (AH) with numerous IgG4-positive cells surrounding it. This case raises the possibility that chronic interstitial inflammation associated with IgG4RD may contribute to the development of renal AH, underscoring the need for further research with additional cases to better understand this relationship.

Indexed as

HemangiomaImmunoglobulin GImmunoglobulin G4-Related DiseaseKidney NeoplasmsAged, 80 and overDiagnosis, DifferentialHumansMaleImmunoglobulin Ganastomosing hemangiomaend-stage renal diseaseIgG4RD-related kidney disease (IgG4RKD)IgG4-related disease (IgG4RD)kidney massrenal malignancy

Identifiers

PMID40399091
PMCPMC12740407

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.