Evidence map›Paper›PMID 40399077›Full record

ArticleInternal medicine (Tokyo, Japan)2025

A Diagnostic Approach to VZV Vasculopathy Using MR Vessel Wall Imaging.

Masaomi Yamamoto, Tomohisa Dembo, Satoru Oji, Kenichi Kaida

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Masaomi YamamotoDepartment of Neurology, Saitama Medical Center, Saitama Medical University, Japan.
Tomohisa DemboDepartment of Neurology, Saitama Medical Center, Saitama Medical University, Japan.
Satoru OjiDepartment of Neurology, Saitama Medical Center, Saitama Medical University, Japan.
Kenichi KaidaDepartment of Neurology, Saitama Medical Center, Saitama Medical University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 43-year-old woman with systemic lupus erythematosus on immunosuppressive therapy developed right hemiparesis and motor aphasia five months after the onset of herpes zoster. Brain magnetic resonance imaging revealed an infarction in the left anterior cerebral artery and severe middle cerebral artery (MCA) stenosis. Despite antiplatelet therapy, recurrent strokes occurred, and vessel wall imaging (VWI) showed circumferential thickening of the MCA, suggesting vasculitis. Cerebrospinal fluid revealed varicella-zoster virus (VZV) deoxyribonucleic acid (DNA) and an elevated anti-VZV IgG index, consistent with VZV vasculopathy. The administration of acyclovir and corticosteroids eliminated VZV DNA. This case highlights the risk of VZV vasculopathy in immunocompromised patients and the usefulness of VWI for its diagnosis.

Indexed as

Herpesvirus 3, HumanHerpes ZosterMagnetic Resonance AngiographyMagnetic Resonance ImagingAdultDNA, ViralFemaleHumansImmunocompromised HostInfarction, Middle Cerebral ArteryLupus Erythematosus, SystemicDNA, Viralcerebral infarctionvaricella zoster virusvasculopathyvessel wall imaging

Identifiers

PMID40399077
PMCPMC12702554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.