ArticleThe Journal of veterinary medical science2025
A newly developed temperature-sensitive Mycoplasma synoviae live attenuated strain prevents pathological lesions of the respiratory and reproductive tracts in chickens caused by a wild-type M. synoviae strain.
Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A field isolate of Mycoplasma synoviae, designated D14-383, caused pathogenic lesions in the air sac, trachea, lung, and ovary and induced a decline or stop in egg production and eggshell apex abnormalities in chickens after intratracheal inoculation. A live M. synoviae vaccine candidate was developed after in vitro passaging at 32°C from a wild-type M. synoviae strain originally isolated from the trachea of a 5-month-old asymptomatic layer chicken. In this study, the vaccine efficacy of the attenuated vaccine candidate strain against M. synoviae infection caused by the D14-383 strain was investigated. Eye-drop vaccination of 4-week-old chickens with 10
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