Evidence map›Paper›PMID 40399066›Full record

ArticleLife science alliance2025

Deep learning models link local cellular features with whole-animal growth dynamics in zebrafish.

Shang-Ru Yang, Megan Liaw, An-Chi Wei, Chen-Hui Chen

Abstract read
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shang-Ru YangGraduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.ORCID 0009-0005-5092-7562
Megan LiawInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan.ORCID 0009-0004-0752-0866
An-Chi WeiGraduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan acwei86@ntu.edu.tw.ORCID 0000-0001-7927-1636
Chen-Hui ChenInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan chcchen@gate.sinica.edu.tw.ORCID 0000-0002-6825-1573

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal growth is driven by the collective actions of cells, which are reciprocally influenced in real-time by the animal's overall growth state. Whereas cell behavior and animal growth state are expected to be tightly coupled, it is not yet determined whether local cellular features at the micrometer scale might correlate with the body size of an animal at the macroscopic level. By inputting 722 skin cell images and corresponding size data for each zebrafish larva into machine learning models, we determined that the Vision Transformer (ViT) with a random cropping and voting strategy was able to achieve high predictive performance (F-score of 0.91). Remarkably, analyzing as few as 27 skin cells within a single image of 0.01 mm

Indexed as

Deep LearningZebrafishAnimalsBody SizeLarvaMachine LearningSkin

Identifiers

PMID40399066
PMCPMC12095864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.