ArticleKorean journal of anesthesiology2026
Changes in pulse wave transit time variability after interscalene brachial plexus block placement.
Article in Korean journal of anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07669688 (Time-Dependent Changes in Pulse Wave Transit Time Following Infraclavicular Block), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Time-Dependent Changes in Pulse Wave Transit Time Following Infraclavicular Block: A Non-Invasive Assessment of Sympathetic Blockade
Who cites it
1 citing paper in PubMed.
- Monitoring sympathectomy in regional anesthesia: pulse wave transit time variability after interscalene block.Korean journal of anesthesiology · 2026Article
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pulse wave transit time (PWTT) increases with decreased vascular tone resulting from sympathetic blockade caused by regional anesthesia. It oscillates, exhibiting variability due to the interaction between the autonomic nervous and cardiovascular systems. We hypothesized that interscalene brachial plexus block (ISBPB) placement increases the PWTT and reduces the low-frequency power of PWTT variability (LF).
methodsFifty-six patients receiving an ISBPB were analyzed. The PWTT was defined as the difference in milliseconds (ms) between the R peak of the electrocardiogram and the peak of the second-derivative photoplethysmographic waveform. The LF was calculated by integrating from 0.04 to 0.15 Hz on the power spectrum obtained from fast Fourier transform. The two variables were collected during the 5 min before the end of acclimatization (baseline), between 5 and 10 min after block needle insertion, and between 15 and 20 min after block needle insertion.
resultsThe PWTT increased significantly (P < 0.001) from baseline (mean [SD]: 155.3 [16.7] ms) to 5-10 min post-needle insertion (166.9 [15.4] ms) (mean difference [MD]: 11.6, 95% CI [9.2-14.0], P < 0.001) and 15-20 min post-needle insertion (165.6 [16.1] ms) (MD: 10.3, 95% CI [7.3-13.2], P < 0.001). The natural log-transformed LF (lnLF) decreased significantly (P < 0.01) from baseline (1.539 [0.560] ln[ms2/Hz]) to 5-10 min post-needle insertion (1.341 [0.617] ln[ms2/Hz]) (MD: -0.198, 95% CI [-0.356 to -0.040], P < 0.01) and 15-20 min post-needle insertion (1.396 [0.548] ln[ms2/Hz]) (MD: -0.144, 95% CI [-0.274 to -0.013], P = 0.03).
conclusionsThe post-ISBPB decrease in lnLF and increase in PWTT may be attributable to ISBPB-induced sympathectomy.
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