Evidence map›Paper›PMID 40398866›Full record

ArticleArquivos de neuro-psiquiatria2025

How the use of FDG PET is improving the diagnosis of dementia in a reference center in Recife, Brazil.

Luisa Couceiro de Albuquerque Macêdo, Raphaelly Ribeiro Campos, Luiz Eduardo Duarte Borges Nunes, Mariana Gonçalves Maciel Pinheiro, Alberto Henrique Torres Trindade da Silva, Maria Regina Vendas Carneiro Leão, Aldson Dos Santos Silva, Felipe Alves Mourato, Simone Cristina Soares Brandão, Breno José Alencar Pires Barbosa

Abstract read
In one paragraph

Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luisa Couceiro de Albuquerque MacêdoUniversidade Federal de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Hospital das Clínicas, Serviço de Neurologia, Recife PE, Brazil.ORCID 0009-0003-5956-9293
Raphaelly Ribeiro CamposUniversidade Federal de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Hospital das Clínicas, Serviço de Neurologia, Recife PE, Brazil.ORCID 0000-0002-0000-3493
Luiz Eduardo Duarte Borges NunesUniversidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.ORCID 0000-0002-8226-2762
Mariana Gonçalves Maciel PinheiroUniversidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.ORCID 0009-0000-0119-1978
Alberto Henrique Torres Trindade da SilvaUniversidade de Pernambuco, Faculdade de Ciências Médicas, Recife PE, Brazil.ORCID 0000-0003-2356-4426
Maria Regina Vendas Carneiro LeãoUniversidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.ORCID 0000-0001-7866-3574
Aldson Dos Santos SilvaUniversidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.ORCID 0009-0005-1873-7435
Felipe Alves MouratoUniversidade Federal de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Hospital das Clínicas, Serviço de Medicina Nuclear, Recife PE, Brazil.ORCID 0000-0001-8102-9654
Simone Cristina Soares BrandãoUniversidade Federal de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Hospital das Clínicas, Serviço de Medicina Nuclear, Recife PE, Brazil.ORCID 0000-0001-9899-1612
Breno José Alencar Pires BarbosaUniversidade Federal de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Hospital das Clínicas, Serviço de Neurologia, Recife PE, Brazil.ORCID 0000-0003-4333-2024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the advent of 18F-2-fluoro-2-deoxy-D-glucose ([18F]FDG, henceforth, FDG) in the 1970s as a neurochemical tracer, FDG positron emission tomography (PET) has been used for research in dementia and to help diagnose dementing neurodegenerative disorders. However, FDG PET is still unavailable in most centers, especially those in low- and middle-income countries, and there is limited data on biomarkers from patients in diverse populations, such Latin Americans.To analyze the main indications and how the use of FDG PET helped improve the diagnosis of dementia in a specialized center in Recife, one of the largest cities in Northeastern Brazil.We retrospectively analyzed data from 62 individuals under follow-up at our center between 2018 and 2023 who had a clinical diagnosis of dementia or mild cognitive impairment and underwent FDG PET scans.In 21/29 (72.4%) patients, FDG PET helped investigate the types of atypical neurodegenerative dementias; in 14/24 (58.3%), it clarified the clinical question in the investigation of early-onset dementia syndromes; and, in 9 cases, it was performed to differentiate between degenerative and non-degenerative dementias.These numbers may set the foundation for further longitudinal analyses and collaborative studies including participants from Northeastern Brazil.

Indexed as

Cognitive DysfunctionDementiaFluorodeoxyglucose F18Positron-Emission TomographyRadiopharmaceuticalsAgedAged, 80 and overBrazilFemaleHumansMaleMiddle AgedRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID40398866
PMCPMC12094862

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.