Evidence map›Paper›PMID 40398865›Full record

ArticleApplied clinical informatics2025

Ambulatory Medication Change Workflows' Effect on Communication to Pharmacies.

Samantha I Pitts, Bridgette Thomas, Yushi Yang, Allen R Chen

Abstract read
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Article in Applied clinical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Samantha I PittsDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Bridgette ThomasJohns Hopkins Care at Home, Johns Hopkins Medicine, Baltimore, Maryland, United States.
Yushi YangJohns Hopkins Armstrong Institute, Johns Hopkins Medicine, Baltimore, Maryland, United States.
Allen R ChenDepartments of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen implemented in both electronic health records (EHRs) and pharmacy management software, CancelRx communicates medication discontinuation in the EHR to pharmacies, which has been demonstrated to reduce medication discrepancies at pharmacies and the risk of medication dispensing after e-prescription discontinuation. Provider workflows for making medication changes and the configuration of CancelRx will affect whether a medication change (e.g., dose adjustment) is communicated to a pharmacy.

objectiveThis study aimed to assess the effect of CancelRx configuration and the EHR tools used in provider workflows for medication changes on notification to health system and external community pharmacies.

methodsWe conducted a functionality analysis of prescriber workflows for documenting a medication change using "change," "reorder," "adjust sig," "discontinue," and "taking differently." In the EHR test environment, we examined three outcomes of interest: communication of discontinuation of the old prescription (or cancellation); generation of a new prescription; and instructions to the patient.

results"Change" was the only single-step function that communicated medication discontinuation to both health system and external community pharmacies with default settings, although "discontinue" followed by a new prescription had the same results. "Reorder" and "adjust sig" functions had different cancellation outcomes for internal and external community pharmacies. "Adjust sig" also had different prescribing outcomes for internal and external pharmacies and "taking differently" did not result in communication of discontinuation or a new prescription at either pharmacy type.

conclusionSeveral workflows for dose changes did not communicate to external community pharmacies, resulting in different prescriptions at the health system and external community pharmacies. Health systems leaders should consider the implications of local EHR workflows and CancelRx configuration on communication of medication changes to pharmacies as part of CancelRx implementation. Multidisciplinary collaboration is needed to develop more effective strategies for communication of medication dose changes.

Indexed as

Ambulatory CareCommunicationPharmaciesWorkflowElectronic Health RecordsHumans

Identifiers

PMID40398865
PMCPMC12094863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.