Evidence map›Paper›PMID 40398711›Full record

ArticleExperimental eye research2025

Functional characterization of Cat

Sindhu Kumari, Tadashi Okamura, Kulandaiappan Varadaraj

Abstract read
In one paragraph

Article in Experimental eye research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CatExperimental eye research · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sindhu KumariPhysiology & Biophysics, Stony Brook University, NY, USA.
Tadashi OkamuraInstitute for Animal Experimentation, Tohoku University School of Medicine, Sendai City, Japan.
Kulandaiappan VaradarajPhysiology & Biophysics, Stony Brook University, NY, USA; Ophthalmology, Stony Brook University, NY, USA. Electronic address: kulandaiappan.varadaraj@stonybrook.edu.

Funding

Roles of Lens Aquaporins and GPX1 in Hydrogen Peroxide Balance, Homeostasis, and AgingR01EY033346 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Kulandaiappan Varadaraj · 2022 to 2026
$1.9M
Role of aquaporins in mammalian lens development,transparency and homeostasisR01EY026155 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI VARADARAJ, KULANDAIAPPAN · 2016 to 2019
$1.6M
NEI NIH HHS R01 EY026155NEI NIH HHS R01 EY033346
6 · The paper itself

Abstract

A natural AQP0 mutation, Cat

Indexed as

AquaporinsCataractEye ProteinsLens, CrystallineMicrophthalmosMutationOxidative StressAnimalsApoptosisDisease Models, AnimalFemaleHydrogen PeroxideMiceOocytesaquaporin 0AquaporinsEye ProteinsHydrogen PeroxideAQP0Cat(Tohm)Congenital lens cataractCytotoxicityDominant negative effectH(2)O(2) transportLensMembrane water permeabilityMicrophthalmiaOxidative stressTg4

Identifiers

PMID40398711
PMCPMC12265049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.