ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025
Impact of angiotensin-converting enzyme inhibition on outcomes after middle meningeal artery embolization in patients with chronic subdural hematoma: A multinational, multi-institutional database study.
Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Reinitiating antiplatelet therapy in chronic subdural hematoma: Does adjunctive middle meningeal artery embolization improve outcomes?Neurosurgical review · 2026Article
- Transverse venous sinus stenting versus cerebrospinal fluid shunting in idiopathic intracranial hypertension: a multi-institutional and multinational database study.Journal of neurointerventional surgery · 2026Article
- Reinitiating anticoagulation in chronic subdural hematomas: does adding middle meningeal artery embolization add value? A multi-institutional, multinational database study.Journal of neurointerventional surgery · 2026Article
- In Reply to the Letter to the Editor Regarding "Standalone Middle Meningeal Artery Embolization versus Medical Management for Chronic Subdural Hematomas: A Multiinstitutional and Multinational Database Study.World neurosurgery · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
BackgroundThe effects of initiating angiotensin-converting enzyme inhibitors (ACEi) in patients with chronic subdural hematoma (cSDH) treated with middle meningeal artery embolization (MMAE) have not been well studied. There is conflicting evidence regarding ACEi use in patients with cSDH who undergo surgery alone, with some studies showing improved outcomes and others showing poorer outcomes. This study presents a real-world, multicenter analysis comparing the outcomes of ACEi reinitiation in this patient cohort.MethodsWe used TriNetX platform to compare outcomes of ACEi initiation in patients with cSDH treated with MMAE. Cohorts were defined using ICD-10 codes. The outcomes included inpatient readmission, need for surgery, and mortality within 6 months following treatment.ResultsA total of 2108 patients with cSDH who underwent MMAE were identified, of whom 251 initiated ACEi within 1 month of treatment. After propensity score matching, patients who received ACEi following MMAE had no significant differences in unplanned readmission (odds ratio (OR): 0.78, 95% confidence interval (CI): 0.54-1.11,
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