Evidence map›Paper›PMID 40397988›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Socioeconomic deprivation is associated with worse in-hospital survival after isolated coronary artery bypass grafting in the UK.

Jeremy Chan, Pradeep Narayan, Jacie Jiaqi Law, Tim Dong, Gianni D Angelini

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Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jeremy ChanBristol Heart Institute, University of Bristol, Bristol, UK.ORCID 0000-0002-3009-5712
Pradeep NarayanRabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, Kolkata, West Bengal, India.ORCID 0009-0005-8984-4473
Jacie Jiaqi LawBristol Heart Institute, University of Bristol, Bristol, UK.ORCID 0009-0009-6460-1060
Tim DongBristol Heart Institute, University of Bristol, Bristol, UK.ORCID 0000-0003-1953-0063
Gianni D AngeliniBristol Heart Institute, University of Bristol, Bristol, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPrevious studies have identified a correlation between socioeconomic deprivation and poorer outcomes following cardiac surgery in the USA, where healthcare is predominantly delivered through private system. However, the influence of socioeconomic deprivation in countries with universal healthcare systems, such as the UK, has been less extensively investigated. Therefore, we used the index of multiple deprivation (IMD) to evaluate the impact of socioeconomic status on early clinical outcomes following coronary artery bypass grafting (CABG) in the UK.

methodsAll patients who underwent elective/urgent isolated CABG between 2008 and 2019 in the UK were included. The IMD, along with other perioperative characteristics, were incorporated into a regression model to determine factors associated with in-hospital mortality.

resultsThe analysis included 182 911 patients (median age: 67.3 years, 82.13% male). Patients were categorized into five groups based on IMD, 1: most deprived to 5 the least: 1 = 30 564, 2 = 30 815, 3 = 59 161, 4 = 31 891 and 5 = 30 480. Patients from the most socioeconomically deprived areas exhibited markedly higher rates of comorbidities and risk factors such as diabetes and had a higher rate of urgent surgical intervention. There is a small increase in in-hospital mortality when socioeconomic status declined, with rates of 1.30, 1.30, 1.24, 1.14 and 1.15% for group 1-5, respectively. Socioeconomic deprivation, particularly in income and education, was associated with an increase in in-hospital survival.

conclusionsSocioeconomic deprivation, particularly in income and education, is associated with higher burdens of comorbidity and a small decrease in-hospital survival after CABG in the UK. This suggests that these factors may play a critical role in clinical outcomes even in a universal healthcare system.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseHospital MortalitySocial DeprivationSocial Determinants of HealthAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited Kingdomcoronary artery bypass graftingindex of multiple deprivationsocioeconomic deprivation

Identifiers

PMID40397988
PMCPMC12202203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.