Evidence map›Paper›PMID 40397828›Full record

Observational studyPlastic and reconstructive surgery2026

Observational Study of Ultrasound-Assisted Liposuction for Lower Limb Lipedema on 191 Female Patients.

Barbara Hersant, Eloi de Clermont-Tonnerre, Giulia Argentino, Malika Bensid, Said Bensaid, Gioanni Roccaro, Oana Hermeziu, Andrea Murante, Simone La Padula, Jean Paul Meningaud

Abstract readObservational Study
In one paragraph

Observational study in Plastic and reconstructive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Muscle Delimitation by Segmental Liposuction: A New Anatomical Approach.Plastic and reconstructive surgery. Global open · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Barbara HersantFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.
Eloi de Clermont-TonnerreFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.
Giulia ArgentinoFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.
Malika BensidDepartment of Anesthesiology, Henri Mondor Hospital, University Paris-Est Crétail.
Said BensaidDepartment of Anesthesiology, Henri Mondor Hospital, University Paris-Est Crétail.
Gioanni RoccaroFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.
Oana HermeziuFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.
Andrea MurantePlastic and Reconstructive Surgery Unit, Università degli Studi di Napoli Federico II.
Simone La PadulaPlastic and Reconstructive Surgery Unit, Università degli Studi di Napoli Federico II.
Jean Paul MeningaudFrom the Department of Plastic, Reconstructive, and Maxillofacial Surgery.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLipedema, a chronic condition affecting 11% of women, causes abnormal fat buildup in the lower limbs, leading to disproportionate body shape and functional problems. Often misdiagnosed, its cause is unclear, and conservative treatments are typically tried first. If these fail, surgical options such as lymphatic-sparing liposuction, including ultrasound-assisted liposuction (UAL), may be considered for lower limb lipedema after 6 months of conservative treatment.

methodsThe authors' cohort included 191 patients with lower limb lipedema (stages 1 to 3) who underwent 2 stages of lymphatic-sparing UAL following 6 months of conservative treatment. Outcome measures included changes in pain assessment using visual analog scale scores, pannus thickness, aesthetic satisfaction, and the documentation of complications before and 12 months after the complete surgical treatment.

resultsThe authors' protocol resulted in significant reductions in circumferences across all assessed regions ( P < 0.001), with an average decrease of -6.396 cm (range, -9.268 to -3.523 cm). Pain levels and sensitivity to touch, bruising, and other discomforts significantly decreased after liposuction (all P < 0.0001). Complication rates were within expected ranges, with no instances of postoperative phlebitis. All patients reported high levels of posttreatment satisfaction.

conclusionsThe integration of a comprehensive medical protocol for managing lipedema, combined with the use of next-generation lymphatic-sparing UAL in 2-stage procedures for the lower limbs, shows promising potential. These findings highlight the effectiveness and safety of liposuction in treating lipedema, providing valuable insights for clinical practice. Long-term follow-up studies are necessary to confirm sustained efficacy.

Indexed as

LipectomyLipedemaUltrasonography, InterventionalAdultAgedFemaleHumansLower ExtremityMiddle AgedPain MeasurementPatient SatisfactionTreatment OutcomeYoung Adult

Identifiers

PMID40397828
PMCPMC13132090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.