Evidence map›Paper›PMID 40397733›Full record

ArticleScience advances2025

Personal care products disrupt the human oxidation field.

Nora Zannoni, Pascale S J Lakey, Youngbo Won, Manabu Shiraiwa, Donghyun Rim, Charles J Weschler, Nijing Wang, Tatjana Arnoldi-Meadows, Lisa Ernle, Anywhere Tsokankunku and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Hydroxyl radical as an indoor oxidant.Environmental science: atmospheres · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nora ZannoniAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0003-2721-5362
Pascale S J LakeyDepartment of Chemistry, University of California, Irvine, CA, USA.ORCID 0000-0003-2923-4073
Youngbo WonDepartment of Architectural Engineering, Pennsylvania State University, University Park, PA, USA.
Manabu ShiraiwaDepartment of Chemistry, University of California, Irvine, CA, USA.ORCID 0000-0003-2532-5373
Donghyun RimDepartment of Architectural Engineering, Pennsylvania State University, University Park, PA, USA.ORCID 0000-0002-0751-3605
Charles J WeschlerInternational Centre for Indoor Environment and Energy, Department of Environmental and Resource Engineering, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0002-9097-5850
Nijing WangAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0003-3197-8151
Tatjana Arnoldi-MeadowsAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0001-6453-9134
Lisa ErnleAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0001-7641-4347
Anywhere TsokankunkuAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0002-0023-7687
Gabriel BeköInternational Centre for Indoor Environment and Energy, Department of Environmental and Resource Engineering, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0001-6107-8336
Pawel WargockiInternational Centre for Indoor Environment and Energy, Department of Environmental and Resource Engineering, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0003-3865-3560
Jonathan WilliamsAtmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.ORCID 0000-0001-9421-1703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People generate hydroxyl radicals (OH) in the presence of ozone via the ozonolysis of skin-emitted alkenes. In this study, we found that the application of personal care products (PCPs) including fragrances and body lotions suppresses the human oxidation field. Body lotion hampers the generation of 6-methyl-5-hepten-2-one, a key OH precursor, while many volatile ingredients of PCPs enhance OH loss in the gas phase. Although fragrances contain terpenes capable of generating OH through ozonolysis, the much larger amount of ethanol solvent acts as a large OH sink. We combined a multiphase chemical kinetic model and a computational fluid dynamics model to demonstrate how the concentrations of the reactive components develop in the indoor environment. These findings have implications for the indoor chemistry of occupied spaces and human health.

Indexed as

CosmeticsHumansHydroxyl RadicalKineticsOxidation-ReductionOzoneCosmeticsHydroxyl RadicalOzone

Identifiers

PMID40397733
PMCPMC12094237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.